Results 131 to 140 of about 1,991,467 (423)

Effect of tendon hydrogel on healing of tendon injury

Experimental and Therapeutic Medicine, 2017
Hand trauma arising from postoperative acute or chronic tendon injuries leads to delayed union and is one of the greatest challenges in clinical practice. The present study hypothesized that an extracellular matrix hydrogel made from tendons can promote tendon healing and improve tissue regeneration.
Quanrong Zhang, Zhenzhong Sun, Yong-jun Rui, Yajun Xu, Zheng Chen, Jiandong Zhou, Xueming Chen   +6 more
openaire   +3 more sources

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Tgfβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration

eLife, 2020
Tendon injuries are common with poor healing potential. The paucity of therapies for tendon injuries is due to our limited understanding of the cells and molecular pathways that drive tendon regeneration.
Deepak A Kaji, Kristen L Howell, Zerina Balic, Dirk Hubmacher, Alice H Huang   +4 more
doaj   +1 more source

HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons [PDF]

, 2013
Platelet-rich plasma (PRP) containing hepatocyte growth factor (HGF) and other growth factors are widely used in orthopaedic/sports medicine to repair injured tendons.
A Mishra, A Schneider, AR Amin, B Christensen, B Christensen, BA Kerr, C Gabay, C Hsu, C Molnar, Cristoforo Scavone, DL Butler, DW Gilroy, DW Gilroy, E Anitua, E Homsi, F Cilli, Freddie H. Fu, G Yang, H El-Sharkawy, Hee-Jeong Im, J Damm, J Zhang, J Zhang, J Zhang, J Zhang, James H-C. Wang, JC Peerbooms, JC Peerbooms, JH Wang, JH Wang, Jianying Zhang, K Takai, Kellie K. Middleton, KM Khan, L Engebretsen, LC Almekinders, M Giannopoulou, M Okada, M Tsuzaki, MH Khan, MM Murray, MM Murray, MM Wolfe, P Bendinelli, P Renstrom, R Gong, RE Marx, RJ de Vos, S Fiorucci, S Nakamura, S Narumiya, SH Ferreira, ST Ferry, T Kaido, T Molloy, TE Foster, TJ Williams, U Sheth, UC Kopp, WL Smith, YH Kang, Z Li   +61 more
core   +1 more source

Biomimetic Microstructured Scaffold with Release of Re‐Modified Teriparatide for Osteoporotic Tendon‐to‐Bone Regeneration via Balancing Bone Homeostasis

Advanced Science, EarlyView.
This study develops RPTH by re‐modifying teriparatide and designs a biomimetic microstructured scaffold (BMRP) loaded with RPTH to address osteoporotic tendon‐to‐bone interface repair. The BMRP restores tissue architecture by balancing bone homeostasis and remodeling the microstructure, achieving functional recovery in an osteoporotic rotator cuff tear
Chengzhong Xu, Sijie Qiu, Zhigen Yuan, Chongyin Qiu, Wenyu Xu, Jialiang Guo, Gen Wen, Shuai Liu, Wenjuan Yan, Haibing Xu, Honghao Hou, Dehong Yang   +11 more
wiley   +1 more source

Motor cortical excitability and pre‐supplementary motor area neurochemistry in healthy adults with substantia nigra hyperechogenicity

Journal of Neuroscience Research, Volume 101, Issue 2, Page 263-277, February 2023., 2023
Substantia nigra (SN) hyperechogenicity, viewed with transcranial ultrasound, is a risk marker for Parkinson's disease. SN hyperechogenicity in healthy older adults is associated with changes in the excitability of specific motor cortical circuitry. These changes are unrelated to glutamate levels in the pre‐supplementary motor area (pre‐SMA).
Gabrielle Todd, Caroline D. Rae, Janet L. Taylor, Nigel C. Rogasch, Jane E. Butler, Michael Hayes, Robert A. Wilcox, Simon C. Gandevia, Karl Aoun, Adrian Esterman, Simon J. G. Lewis, Julie M. Hall, Elie Matar, Jana Godau, Daniela Berg, Christian Plewnia, Anna‐Katharina von Thaler, Clarence Chiang, Kay L. Double   +18 more
wiley   +1 more source

Long-term Results after Restoring Flexor Tendon Injury in Children Younger than Age 10 Years [PDF]

, 2016
Background: In regard to the rarity of pediatric tendon lacerations compared with the adult population, sparse knowledge exists. Published reports indicate that the incidence of “good” flexor tendon repair outcomes is low.
Jafari, Davod, Nabi, Razieh, Najd-Mazhar, Farid, Shariatzadeh, Hooman   +3 more
core   +1 more source

Associations between poor oral health and reinjuries in male elite soccer players : a cross-sectional self-report study [PDF]

, 2015
Background: Although it is well known that oral pathogens can enter the systemic circulation and cause disease, it is largely unknown if poor oral health increases the risk of sports injuries.
Goedhart, Arnold, Solleveld, Henny, Vanden Bossche, Luc   +2 more
core   +1 more source

Strong and Fatigue‐Resistant Hydrogels via Poor Solvent Evaporation Assisted Hot‐Stretching for Tendon Repair

Advanced Science, EarlyView.
An anisotropic hydrogel (AHs) is prepared in this study. The strength of AHs can reach up to 33.14 ± 2.05 MPa, and it exhibits unique defect‐insensitive characteristics. Cracks can only deflect along the fiber alignment direction, demonstrating an interesting self‐protection function.
Huamin Li, Ying Zhang, Haidi Wu, Zhanqi Liu, Cheng Guan, Jin Zhang, Jingyi Chen, Shaohua He, Xuewu Huang, Wancheng Gu, Yiu Wing Mai, Jiefeng Gao   +11 more
wiley   +1 more source

Shape differences in the semitendinosus following tendon harvesting for anterior cruciate ligament reconstruction

Journal of Orthopaedic Research, Volume 41, Issue 1, Page 44-53, January 2023., 2023
Abstract Following hamstring autograft anterior cruciate ligament reconstruction (ACLR), muscle length, cross‐sectional area, and volume are reduced. However, these discrete measures of morphology do not account for complex three‐dimensional muscle shape. The primary aim of this study was to determine between‐limb semitendinosus (ST) shape and regional
William du Moulin, Matthew Bourne, Laura E. Diamond, Jason Konrath, Christopher Vertullo, David Lloyd, David J. Saxby   +6 more
wiley   +1 more source