Results 21 to 30 of about 19,346 (104)

Novel strategies in tendon and ligament tissue engineering: Advanced biomaterials and regeneration motifs

Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology, 2010
Tendon and ligaments have poor healing capacity and when injured often require surgical intervention. Tissue replacement via autografts and allografts are non-ideal strategies that can lead to future problems.
Kuo Catherine K, Marturano Joseph E, Tuan Rocky S   +2 more
doaj   +1 more source

New frontiers of tendon augmentation technology in tissue engineering and regenerative medicine: a concise literature review

Journal of International Medical Research, 2022
Tissue banking programs fail to meet the demand for human organs and tissues for transplantation into patients with congenital defects, injuries, chronic diseases, and end-stage organ failure.
Rangarirai Makuku, Jean-David Werthel, Leila Oryadi Zanjani, Mohammad Hossein Nabian, Marcarious M. Tantuoyir   +4 more
doaj   +1 more source

Clinical perspectives for repairing rotator cuff injuries with multi-tissue regenerative approaches

Journal of Orthopaedic Translation, 2022
Background: In the musculoskeletal system, bone, tendon, and muscle form highly integrated multi-tissue units such as the rotator cuff complex, which facilitates functional and dynamic movement of the shoulder joint. Understanding the intricate interplay
Xu Zhang, Dan Wang, Zuyong Wang, Samuel Ka-kin Ling, Patrick Shu-hang Yung, Rocky S. Tuan, Dai Fei Elmer Ker   +6 more
doaj   +1 more source

Scaffold-Mediated Immunoengineering as Innovative Strategy for Tendon Regeneration

Cells, 2022
Tendon injuries are at the frontier of innovative approaches to public health concerns and sectoral policy objectives. Indeed, these injuries remain difficult to manage due to tendon’s poor healing ability ascribable to a hypo-cellularity and low ...
Valentina Russo, Mohammad El Khatib, Giuseppe Prencipe, Adrián Cerveró-Varona, Maria Rita Citeroni, Annunziata Mauro, Paolo Berardinelli, Melisa Faydaver, Arlette A. Haidar-Montes, Maura Turriani, Oriana Di Giacinto, Marcello Raspa, Ferdinando Scavizzi, Fabrizio Bonaventura, Liliana Liverani, Aldo R. Boccaccini, Barbara Barboni   +16 more
doaj   +1 more source

Dexamethasone Is Not Sufficient to Facilitate Tenogenic Differentiation of Dermal Fibroblasts in a 3D Organoid Model

Biomedicines, 2023
Self-assembling three-dimensional organoids that do not rely on an exogenous scaffold but maintain their native cell-to-cell and cell-to-matrix interactions represent a promising model in the field of tendon tissue engineering.
Niklas Kroner-Weigl, Jin Chu, Maximilian Rudert, Volker Alt, Chisa Shukunami, Denitsa Docheva   +5 more
doaj   +1 more source

Biomarkers for tissue engineering of the tendon-bone interface. [PDF]

PLoS ONE, 2018
The tendon-bone interface (enthesis) is a highly sophisticated biomaterial junction that allows stress transfer between mechanically dissimilar materials.
Lara A Kuntz, Leone Rossetti, Elena Kunold, Andreas Schmitt, Ruediger von Eisenhart-Rothe, Andreas R Bausch, Rainer H Burgkart   +6 more
doaj   +1 more source

Engineering Musculoskeletal Grafts for Multi-Tissue Unit Repair: Lessons From Developmental Biology and Wound Healing

Frontiers in Physiology, 2021
In the musculoskeletal system, bone, tendon, and skeletal muscle integrate and act coordinately as a single multi-tissue unit to facilitate body movement.
Xu Zhang, Xu Zhang, Dan Wang, Dan Wang, Dan Wang, Dan Wang, King-Lun Kingston Mak, Rocky S. Tuan, Rocky S. Tuan, Dai Fei Elmer Ker, Dai Fei Elmer Ker, Dai Fei Elmer Ker, Dai Fei Elmer Ker   +12 more
doaj   +1 more source

Leveraging in vivo animal models of tendon loading to inform tissue engineering approaches

Frontiers in Bioengineering and Biotechnology
Tendon injuries disrupt successful transmission of force between muscle and bone, resulting in reduced mobility, increased pain, and significantly reduced quality of life for affected patients. There are currently no targeted treatments to improve tendon
Samantha Muscat, Samantha Muscat, Anne E. C. Nichols   +2 more
doaj   +1 more source

Electrospun aligned poly(ε-caprolactone) nanofiber yarns guiding 3D organization of tendon stem/progenitor cells in tenogenic differentiation and tendon repair

Frontiers in Bioengineering and Biotechnology, 2022
Hierarchical anisotropy structure directing 3D cellular orientation plays a crucial role in designing tendon tissue engineering scaffolds. Despite recent development of fabrication technologies for controlling cellular organization and design of ...
Qiao Yang, Jianfeng Li, Jianfeng Li, Weiwei Su, Liu Yu, Ting Li, Yongdi Wang, Kairui Zhang, Yaobin Wu, Ling Wang   +9 more
doaj   +1 more source

Natural, synthetic and commercially-available biopolymers used to regenerate tendons and ligaments

Bioactive Materials, 2023
Tendon and ligament (TL) injuries affect millions of people annually. Biopolymers play a significant role in TL tissue repair, whether the treatment relies on tissue engineering strategies or using artificial tendon grafts.
Behzad Shiroud Heidari, Rui Ruan, Ebrahim Vahabli, Peilin Chen, Elena M. De-Juan-Pardo, Minghao Zheng, Barry Doyle   +6 more
doaj   +1 more source