Results 81 to 90 of about 6,025 (196)

Intravenous tenecteplase compared with alteplase for minor ischaemic stroke: a secondary analysis of the AcT randomised clinical trial

Stroke and Vascular Neurology
Background In ischaemic stroke, minor deficits (National Institutes of Health Stroke Scale (NIHSS) ≤5) at presentation are common but often progress, leaving patients with significant disability.
Dar Dowlatshahi, Mohammed A Almekhlafi, Tolulope Sajobi, Aleksandra Pikula, Ashfaq Shuaib, Alexandre Y Poppe, Richard H Swartz, Fouzi Bala, Ibrahim Alhabli, Aleksander Tkach, Heather Williams, Shelagh B Coutts, Nishita Singh, Anurag Trivedi, Andrew Demchuk, Gary Hunter, Brian H Buck, Faysal Benali, Bijoy Menon, MacKenzie Horn, Radhika Nair, Thalia Field, Mahesh Kate, Negar Asdaghi, Robert Sarmiento, Ayoola Ademola, Houman Khosravani, Herbert Alejandro Manosalva Alzate, Luciana Catanese   +28 more
doaj   +1 more source

Estudo da associação entre a ativação da resposta inflamatória sistêmica na fase aguda do infarto do miocárdio com supradesnivelamento do segmento ST e a zona peri-infarto, definida por ressonância magnética [PDF]

, 2013
Tese (doutorado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Ciências Médicas, 2013.Introdução: O aumento da atividade inflamatória sistêmica (AIS) durante o infarto domiocárdio (IM) está diretamente associado à ...
Silva, José Carlos Quinaglia e
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Concomitant pulmonary embolism and aortic dissection: approach to anticoagulation [PDF]

, 2018
Os autores descrevem um caso de uma doente admitida após episódio pré-sincopal associado a precordialgia e cujo ecocardiograma sumário feito no Servic¸o de Urgência demonstrou alterac¸ões compatíveis com tromboembolismo pulmonar, tendo a doente sido ...
Augusto, J, Magno, P, Ministro, A, Morais, C, Roque, D, Santos, M, Sousa, M   +6 more
core   +1 more source

Risk of angioedema and thrombolytic therapy among stroke patients: An analysis of data from the FDA Adverse Event Reporting System database

Neurotherapeutics
The angioedema risk may vary among stroke patients receiving different thrombolytic agents. This study aimed to investigate the angioedema risk associated with different thrombolytic agents and to identify associated risk factors.
Hunong Xiang, Yu Ma, Xiaochao Luo, Jian Guo, Minghong Yao, Yanmei Liu, Ke Deng, Xin Sun, Ling Li   +8 more
doaj   +1 more source

Ethnic Differences in the Safety and Efficacy of Tenecteplase Versus Alteplase for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis [PDF]

Journal of Stroke
Background and Purpose Tenecteplase is a thrombolytic agent with pharmacological advantages over alteplase and has been shown to be noninferior to alteplase for acute ischemic stroke in randomized trials.
Jin Hean Koh, Claire Yi Jia Lim, Lucas Tze Peng Tan, Ching-Hui Sia, Kian Keong Poh, Vijay Kumar Sharma, Leonard Leong Litt Yeo, Andrew Fu Wah Ho, Teddy Wu, William Kok-Fai Kong, Benjamin Yong Qiang Tan   +10 more
doaj   +1 more source

Uso de trombolíticos e associações farmacológicas no tratamento do acidente vascular cerebral isquêmico agudo : revisão sistemática e meta-análise em rede [PDF]

, 2017
Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2017.Introdução: O acidente vascular cerebral isquêmico (AVCi) é uma das principais causas de mortalidade e incapacidade ...
Brito, Gabriela Vilela de
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Randomized trial of inhaled nitric oxide to treat acute pulmonary embolism: The iNOPE trial [PDF]

, 2017
BACKGROUND: The study hypothesis is that administration of inhaled nitric oxide (NO) plus oxygen to subjects with submassive pulmonary embolism (PE) will improve right ventricular (RV) systolic function and reduce RV strain and necrosis, while ...
Hall, Cassandra L., Jones, Alan E., Kline, Jeffrey A., Lahm, Tim, Mastouri, Ronald, Puskarich, Michael A.   +5 more
core   +1 more source

Spinal subdural hematoma as a complication of tenecteplase treatment for acute ischemic stroke: A case report

Heliyon
Intravenous thrombolysis is an effective treatment for acute ischemic stroke. The ESO recommends that tenecteplase be used for thrombolytic therapy in stroke within 4.5h of onset.
Sisi Zhao, Lingtao Tang, Yanpeng Lu, Yingyi Li   +3 more
doaj   +1 more source

Design of a recombinant tissue plasminogen activator production plant [PDF]

, 2013
Conté: Part 1, General vision and presentation of the plant / Ferran Vila. Part 2, Technical characteristics of the process / Carla Sánchez.
Roca, Ramon, Sánchez, Carla, Universitat Autònoma de Barcelona. Facultat de Biociències, Vila, Ferran   +3 more
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Comparison between zofenopril and ramipril in combination with acetylsalicylic acid in patients with left ventricular systolic dysfunction after acute myocardial infarction: results of a randomized, double-blind, parallel-group, multicenter, European study (SMILE-4) [PDF]

, 2012
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEIs) are largely employed for treating patients with left ventricular dysfunction (LVD), but their efficacy may be negatively affected by concomitant administration of acetylsalicylic acid (ASA),
Claudio Borghi, Dragos Vinereanu, Ettore Ambrosioni, Giuseppe Ambrosio, null null, Salvatore Novo   +5 more
core   +1 more source