Cobicistat Versus Ritonavir as a Pharmacoenhancer of Atazanavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment-Naive HIV Type 1-Infected Patients: Week 48 Results [PDF]
Background. Cobicistat (COBI) is a pharmacoenhancer with no antiretroviral activity in vitro. Methods. An international, randomized, double-blind, double-dummy, active-controlled trial was conducted to evaluate the efficacy and safety of COBI versus ...
Andrade-Villanueva, Jaime +15 more
core
HIV Protective Efficacy and Correlates of Tenofovir Blood Concentrations in a Clinical Trial of PrEP for HIV Prevention [PDF]
Background: Antiretroviral pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy for which adherence is a known determinant of efficacy. Blood concentrations of PrEP medications are one objective marker of adherence.
Baeten, Jared M. +10 more
core +1 more source
Dyslipidemia in chronic hepatitis B patients on tenofovir alafenamide: Facts and puzzles [PDF]
Hung-Yao Lin, Tai-Chung Tseng
doaj +1 more source
Clinical and Translational Science, Volume 19, Issue 5, May 2026.
Inès Ben Ghezala, Marc Bardou
wiley +1 more source
Jing Li,1 Donghua Zhang,1 Xinxin Zhang1,2 1Department of Infectious Diseases, Research Laboratory of Clinical Virology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Sino-French Research ...
Li J, Zhang D, Zhang X
doaj
Promising Drugs Require Proper Testing
Clinical and Translational Science, Volume 19, Issue 5, May 2026.
Jean‐Jacques Parienti
wiley +1 more source
Background and objectives: Low bone mineral density (BMD) is a recognized complication in people living with HIV (PLHIV) that remains under-addressed, particularly in Malaysia.
Muhamad Riduan Daud +7 more
doaj +1 more source
The role of drug resistance in poor viral suppression in rural South Africa: findings from a population-based study. [PDF]
BACKGROUND:Understanding factors driving virological failure, including the contribution of HIV drug resistance mutations (DRM), is critical to ensuring HIV treatment remains effective.
Barnhart, Scott +9 more
core
HIV and CKD in the Tenofovir Era: A Prospective Parallel-Group Cohort Study From Tanzania
Rationale & Objective: Longitudinal research on chronic kidney disease (CKD) in sub-Saharan Africa is sparse, especially among people living with HIV (PLWH).
Nicholas L.S. Roberts +11 more
doaj +1 more source
An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs [PDF]
Objectives: HIV-1 subtype C might have a greater propensity to develop K65R mutations in patients with virological failure compared with other subtypes. However, the strong association between viral subtype and confounding factors such as exposure groups
Churchill, D +13 more
core

