Results 11 to 20 of about 12,401 (156)

Effect of Tenofovir Disoproxil Fumarate and Emtricitabine on nasopharyngeal SARS-CoV-2 viral load burden amongst outpatients with COVID-19: A pilot, randomized, open-label phase 2 trial

EClinicalMedicine, 2021
Background: Tenofovir and emtricitabine interfere with the SARS CoV-2 ribonucleic acid (RNA)-dependent RNA polymerase (RdRp). Several cohorts reported that people treated by tenofovir disoproxil fumarate and emtricitabine are less likely to develop SARS ...
Jean-Jacques Parienti, Thierry Prazuck, Laure Peyro-Saint-Paul, Anna Fournier, Cécile Valentin, Sylvie Brucato, Renaud Verdon, Aymeric Sève, Mathilda Colin, Fabien Lesne, Jérome Guinard, Meriadeg Ar Gouilh, Julia Dina, Astrid Vabret, Laurent Hocqueloux   +14 more
doaj   +1 more source

Method development and validation for multi-component analysis of lamivudine & tenofovir disoproxil fumarate in bulk drug by UV-visible spectrophotometer & RP-HPLC

Journal of Applied Pharmaceutical Research, 2020
A novel, simple, precise and accurate method developed for the estimation of Lamivudine and tenofovir disoproxil fumarate (TDF) in bulk drug form has been established. Lamivudine and tenofovir are well known drugs and used in treatment of HIV- Ⅰ.
Shweta Sharma, Amar Deep Ankalgi, Pooja Kaushal, M. S. Ashawat   +3 more
doaj   +1 more source

Evaluation of genotoxic activity of tenofovir disoproxil fumarate in human peripheral lymphocytes

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Purpose: Antiretroviral drugs used in the treatment of HIV (Human Immunodeficiency Virus) iinfection, treat by preventing the proliferation of HIV in human body.
Kubra Kurt, Lale Donbak, Ahmet Kayraldiz
doaj   +1 more source

Tenofovir alafenamide fumarate

Antiviral Therapy, 2022
Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue resulting in high concentrations of tenofovir (TFV) and its active diphosphate metabolite inside the cells that replicate HIV. Due
William A Lee, Andrew K Cheng
doaj   +1 more source

Assessing bone mineral density in children and adolescents living with HIV and on treatment with tenofovir disoproxil fumarate: a systematic review

Revista Paulista de Pediatria, 2023
Objective: To investigate the impact of tenofovir disoproxil fumarate on bone mineral density and bone mineral content in children and adolescents infected with the human immunodeficiency virus.
Maria Brennda Ferreira de Gusmão, Vinícius Vital de Oliveira, Natália Maria da Silva Santos, Luciana Costa Melo   +3 more
doaj   +1 more source

Concurrent estimation of lamivudine, tenofovir disoproxil fumarate, and efavirenz in blended mixture and triple combination tablet formulation by a new stability indicating RP-HPLC method

Future Journal of Pharmaceutical Sciences, 2021
Background An easy, defined, rapid, and accurate reverse phase high-performance liquid chromatography method was developed and subsequently validated for the concurrent estimation of lamivudine, efavirenz, and tenofovir disoproxil fumarate in their pure ...
Ramreddy Godela, Vijayalaxmi Kammari, Sowjanya Gummadi, Durgaprasad Beda   +3 more
doaj   +1 more source

Tenofovir Disoproxil Fumarate

Reactions Weekly, 2006
europepmc   +2 more sources

Efficacy and safety of Tenofovir Disoproxil Fumarate in Patients with Chronic Hepatitis B with High Baseline Viral Load

SVU - International Journal of Medical Sciences, 2020
Background: Chronic hepatitis B virus infection is an important cause of morbidity and mortality. Tenofovir disoproxil fumarate was licensed for the treatment of hepatitis B virus infection. So, the current study aimed to Evaluate efficacy and outcome of
Ahmed Gad Mohamed Ahmed*, Ali Abdel Rahman Sayed Ghweil, Hasan Sedeek Mahmoud   +2 more
doaj   +1 more source

Effects of Hydrochlorothiazide on Tenofovir Disoproxil Fumarate-Induced Nephrotoxicity in Rats

Iraqi Journal of Pharmaceutical Sciences, 2019
Tenofovir disoproxil fumarate, a nucleotide reverse transcriptase inhibitor utilized for the treatment of hepatitis B virus and human immunodeficiency virus infections; and is now one of the most widely used antiretroviral drug.
Iman G.Al-Rakhat, Nada N.Al-Shawi
doaj   +1 more source

A Simple RP-HPLC Method to Simultaneously Assay the Contents of Lamivudine, Tenofovir, and Nevirapine in Fixed Dose Combined Oral Antiviral Medicines

Journal of Chemistry, 2020
An accurate and rapid reverse HPLC method has been developed and validated for the simultaneous quantification of lamivudine, nevirapine, and tenofovir disoproxil fumarate.
Phoebe Esinam Goku, Emmanuel Orman, Anna Naa Kwarley Quartey, Joseph Kwasi Adu, Reimmel Kwame Adosraku   +4 more
doaj   +1 more source