Results 61 to 70 of about 5,418,578 (179)

Localized type tenosynovial giant cell tumor with metastases to lungs and pleura: a case report and literature review

Journal of Medical Case Reports
Background Tenosynovial giant cell tumor is a rare soft tissue tumor of the synovium of joint, bursae, or tendon sheath. It is divided into localized or diffuse types on the basis of the growth pattern.
Afshan Ali Shaik, Manoj Kumar Panigrahi, Mahismita Patro, Vangapandu Sushmita, Pritinanda Mishra   +4 more
doaj   +1 more source

Intramuscular Tenosynovial Giant Cell Tumor, Diffuse-Type [PDF]

Journal of Pathology and Translational Medicine, 2016
Tenosynovial giant cell tumors (TSGCT), a group of tumors that originate in tendon sheaths, joints, bursae, or adjacent soft tissue, were first described in 1941 by Jaffe et al. [1]. Diffuse-type TSGCT are known to be located in the periarticular soft tissue, while pure intramuscular tumors are rare.
Yoo Jin Lee, Youngjin Kang, Jiyoon Jung, Seojin Kim, Chul Hwan Kim   +4 more
openaire   +3 more sources

Fat‐Containing Soft Tissue Lesions of the Limbs and Body Wall—A Pictorial Essay

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Lipomatous tumours are frequently encountered on imaging. The spectrum of lipomatous tumours ranges from simple lipomas, which can be monitored clinically, to high‐grade liposarcomas, which require timely, multidisciplinary management. The presence of fat within lesions may also be observed in non‐lipomatous tumours, as well as in a variety of
Kai‐Zheong Lim, Cathryn Hui
wiley   +1 more source

Prevalence and Risk Factors for Financial Toxicity Among Sarcoma Patients During and Following Treatment Across the Lifespan

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Financial toxicity (FT) describes the impact of cancer and treatment‐related financial burden. We evaluated the prevalence and risk factors for FT among sarcoma patients. Methods A sarcoma cohort was constructed to assess health outcomes.
Michael J. Robinson, Lili Sun, Tatsuki Koyama, Emma A. Schremp, Grace Aronoff, Tulio Guimaraes, Taylor A. Stokes, Elizabeth J. Davis, Vicki Keedy, Scott C. Borinstein, Herbert S. Schwartz, Jennifer L. Halpern, Joshua M. Lawrenz, Daniel Johnson, Timothy Su, Leo Luo, Travis Osterman, Tuya Pal, Ben H. Park, Xiao‐Ou Shu, Debra L. Friedman, Eric T. Shinohara   +21 more
wiley   +1 more source

UTMD Suppresses CSF‐1 to Drive Macrophage‐Mediated Ferroptosis in Papillary Thyroid Carcinoma

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT The tumor microenvironment (TME) of Papillary Thyroid Carcinoma (PTC), particularly the role of tumor‐associated macrophages (TAMs), contributes to therapeutic resistance. This study investigated whether ultrasound‐targeted microbubble destruction (UTMD), a non‐invasive physical modality, could reprogram the TME through modulation of TAMs and ...
Yanqiang Niu, Zhenqiang Yao, Minghua Zhang, Jiayan Zhang, Yushan Li, Jinhui Xie, Zubang Zhou   +6 more
wiley   +1 more source

Optimal Treatment for Tenosynovial Giant Cell Tumor of the Hand

Journal of Nippon Medical School, 2020
This review examines the following aspects of tenosynovial giant cell tumors (TSGCTs): the use of multiple names, the complex relationship between tumor growth pattern and location, the high rate of postoperative recurrence, local invasiveness, use of nonsurgical therapy with molecularly targeted drugs, and best current treatments.
Kitagawa, Yasuyuki, Takai, Shinro
openaire   +3 more sources

Vimseltinib for patients with tenosynovial giant cell tumor: A multicenter, open‐label, phase 2 trial

Cancer, Volume 132, Issue 17, 1 September 2026.
Abstract Background Tenosynovial giant cell tumor (TGCT) is a locally aggressive neoplasm caused by dysregulation of the colony‐stimulating factor 1 (CSF1) gene. Patients report substantial pain, stiffness, and declining physical function; those whose disease is not amenable to surgery require systemic therapy.
Silvia Stacchiotti, Jean‐Yves Blay, Piotr Rutkowski, Hans Gelderblom, Alejandro Falcón, Axel Le Cesne, Jayesh Desai, Emanuela Palmerini, César Serrano, Kristen N. Ganjoo, Gina Z. D’Amato, Christopher W. Ryan, Breelyn A. Wilky, Virginia Ferraresi, Ramy Saleh, Vinod Ravi, Albiruni Abdul Razak, Antonio Casado Herráez, Mahbubl Ahmed, Nicholas M. Bernthal, Michiel van de Sande, Mehdi Brahmi, Bartlomiej Szostakowski, Jasmine Sen, Nicholas A. Zeringo, Brooke Harrow, Supraja Narasimhan, Amanda Saunders, Maitreyi G. Sharma, Matthew L. Sherman, Andrew J. Wagner, William D. Tap   +31 more
wiley   +1 more source

Diffuse-Type Tenosynovial Giant Cell Tumor of the Knee with Concurrent Polymicrobial Infection (Klebsiella oxytoca and Group B Streptococcus)

Case Reports in Infectious Diseases, 2021
Tenosynovial giant cell tumors (TGCT) are a rare class of benign proliferative tumors that are classified according to their presentation: localized-type (L-TGCT) or diffuse-type (D-TGCT).
J. Hunter Marshall, John G. Skedros, Chris F. Campana, Allan M. Seibert   +3 more
doaj   +1 more source

Diffuse‐Type Tenosynovial Giant Cell Tumor of the Hip With Acetabular Bone Involvement: A Case Report With Radiologic‐Pathologic Correlation

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Diffuse‐type tenosynovial giant cell tumor (D‐TGCT) is an uncommon synovial neoplasm. Hip involvement is rare and may be difficult to recognize because symptoms are nonspecific and osseous erosion can mimic more aggressive infectious, inflammatory, or neoplastic processes.
Wang Quanbing, Xing Huanhuan, Zhang Xing, Yang Tao, Zhang Jun, Zhu Lei, Li Kai, Luo Lei, Ao Feng, Yang Wei   +9 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source