Results 111 to 120 of about 884,374 (267)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Elastic-plastic behaviour of AISiC metal matrix composite rod under combined tension and torsion loading [PDF]

open access: yes, 2003
Most machine components and structural members are subjected to complex loading conditions during service. Typical complex loading conditions can be observed in the case of a bolt When a bolt is tightened to bring machine components together, stresses ...
Raghupathy, Padmanabhan
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Numerical Investigation of the Undrained Compression and Pull-Out Capacity of Suction Foundations in Clay

open access: yesPolish Maritime Research, 2015
This paper presents the results of three-dimensional finite difference analysis of suction foundations in uniform and non-uniform clays under undrained conditions. The Tresca criterion was used to simulate the stress-strain response. The bearing capacity
Du Jiaqing   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Surface Tension Matthew Buckingham, Nina Canell & Robin Watkins, Youngmi Chun, Kelly Jazvac, Sreshta Rit Premnath, Jimmy Robert, Mark Soo [PDF]

open access: yes, 2013
Over the past decade, digital media has transformed how we take pictures, how existing images circulate in the world and how histories are written. While many artists have questioned where to locate images in our contemporary context, their ongoing ...
Jazvac, Kelly   +8 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Convertisseur de tension DC/DC muni d’un dispositif coupe-circuit [PDF]

open access: yes, 2019
Convertisseur de tension DC/DC muni d’un dispositif coupe-circuit Convertisseur de tension (10) comportant au moins un bras (24) s’étendant entre un premier terminal continu (16) et un deuxième terminal continu (28) et comportant au moins un demi-bras ...
Dworakowski, Piotr   +5 more
core  

In situ tension-tension strain path changes of cold-rolled Mg AZ31B [PDF]

open access: yes
The mechanical behavior of cold-rolled Mg AZ31B is studied during in-plane multiaxial loading and tension-tension strain path changes performed on cruciform samples using in situ neutron diffraction and EBSD.
Van Petegem, S.   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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