Results 111 to 120 of about 883,383 (317)
Elastic-plastic behaviour of AISiC metal matrix composite rod under combined tension and torsion loading [PDF]
, 2003 Most machine components and structural members are subjected to complex loading conditions during service. Typical complex loading conditions can be observed in the case of a bolt When a bolt is tightened to bring machine components together, stresses ...
Raghupathy, Padmanabhan
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
This meter measures the force needed to lift a metal ring from the surface of a liquid by way of a torsion wire.
Central Scientific Company
core
Polish Maritime Research, 2015 This paper presents the results of three-dimensional finite difference analysis of suction foundations in uniform and non-uniform clays under undrained conditions. The Tresca criterion was used to simulate the stress-strain response. The bearing capacity
Du Jiaqing +3 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Tension-free H0 from evanescent dark energy
, 2018 A tension free estimate of H0~74 km/s/Mpc is derived from cosmological data H(z) based on a stress-energy tensor of the cosmological vacuum induced by thermodynamic properties of the cosmological horizon, that defines the phase space of FRW-cosmologies ...
Maurice H.P.M. van Putten +1 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
In situ tension-tension strain path changes of cold-rolled Mg AZ31B [PDF]
The mechanical behavior of cold-rolled Mg AZ31B is studied during in-plane multiaxial loading and tension-tension strain path changes performed on cruciform samples using in situ neutron diffraction and EBSD.
Van Petegem, S. +5 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source