Results 91 to 100 of about 2,639,223 (300)
Spatial string tension revisited
, 2005 The spatial string tension, a classic non-perturbative probe for the convergence of the weak-coupling expansion at high temperatures, can be determined in full QCD as well as in a dimensionally reduced effective theory. Comparing both approaches, we find
Laine, M., Schroder, Y.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
中西医结合护理Objective To analyze the current situation and influencing factors of work engagement of neurology nurses. Methods Using the convenient sampling method, a cross-sectional survey was conducted among nurses in the department of neurology in a Class III ...
FU Jing (富晶) +5 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Кубанский научный медицинский вестник, 2015 It studied 764 patients with widespread peritonitis shows the benefits of treatment relaparotomy-programmed with the closing of the surgical wound with removable draining musculoaponeurotic seams (RDMAS).
V. M. Bensman +8 more
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Journal of Academia, 2022 This study aims to evaluate the efficiency of the regularized and tension spline interpolation methods to predict and map the concentration of nitrate on the surface water of Pulau Tuba, Langkawi. Kedah.
Sharir Aizat Kamaruddin
doaj
, 2008 The development and availability of Information Communication Technology (ICT) impacts many sectors yet a digital divide is still present amongst citizens in communities.
Parker, Marlon +2 more
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
CORRUPTION AND PSYCHOSOCIAL DISSONANCE IN ACADEMIC-PROFESSIONAL ACTIVITY
Russian Journal of Economics and Law, 2013 The notion of cognitive dissonance, introduced by L.Festinger, does take into account the multiple factors of social interaction. The author introduces the general notion of “psycho-social dissonance” as discrepancy between individual or group ...
V. V. Vasina
doaj