Results 91 to 100 of about 1,582,483 (298)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Kalman-Filter-Based Tension Control Design for Industrial Roll-to-Roll System
Algorithms, 2019 This paper presents a robust and precise tension control method for a roll-to-roll (R2R) system. In R2R processing, robust and precise tension control is very important because improper web tension control leads to deterioration in the quality of web ...
Hyeongjin Hwang +3 more
doaj +1 more source
Yarn Tension Control of Winding Machine Using Active Tensioner
Journal of Institute of Control, Robotics and Systems, 2008 This paper is devoted to yarn tension control problem in winding machines. The passive take-up unit is replaced by active one with ADRC(Active Disturbance Rejection Control) and it was compared with the method using conventional PD(Proportional￢Derivative) controller.
openaire +2 more sources
Low gravity propellant control using capillary devices in large scale cryogenic vehicles - Related IRAD studies [PDF]
Low gravity propellant control by capillary devices in cryogenic vehicles - screen flow tests, bubble dynamics, residual analysis, settling, and surface tension ...
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Design and Analysis of a Novel Tension Control Method for Winding Machine
Chinese Journal of Mechanical Engineering, 2018 Filament winding has emerged as the main process for carbon fiber reinforced plastic (CFRP) fabrication, and tension control plays a key role in enhancing the quality of the winding products.
Xiao-Ming Xu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
ブドウ‘マスカット・オブ・アレキサンドリア’に対する潅水制限が樹体の水分，葉温，果実温，果実の全フェノール含量，果皮色に及ぼす影響 [PDF]
, 2007 Effects of different deficit irrigation strategies on vine water status, canopy and cluster temperatures, fruit total phenolics, and the color of white table grapes (Vitis vinifera L., cv.
Diaa Osama, El-Ansary, Okamoto, Goro
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Applied SciencesTension control in cold-rolling pilot mills (CRPMs) with hydraulic tension is subject to extraneous forces resulting from positional disturbances, strong coupling, and time-varying characteristics, making it challenging to achieve ideal control results ...
Guiqiao Wang +3 more
doaj +1 more source