Results 101 to 110 of about 361,101 (305)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Multi-Span Tension Control for Printing Systems in Gravure Printed Electronic Equipment
Applied SciencesThe tension system is one of the most critical systems in gravure printed electronic equipment. It possesses a complex structure that spans the entire feeding process, from unwinding through printing to rewinding.
Kui He +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Yarn tension control technique for improving polyester soft winding process. [PDF]
Sci Rep, 2021 Ali M, Ahmed R, Amer M.
europepmc +1 more source
On the Tension Control of Warping Machine
Journal of the Textile Machinary Society, 1956 研究目的整経機において, 摩擦棒と経糸との接触角を積極的に変化させることにより, 終始等張力で経糸を巻き取る方法を考案し, モデル実験と理論的考察を行った.研究結果本研究に用いた装置のごとき機構において等張力で経糸を巻き取るためには摩擦棒を取り付けた腕を一定速度で布との接触角を減少させる方向に回転させればよいことがわかった.
Inoue, T., Nishioka, T., Ohmori, M.
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Rat in vitro spermatogenesis promoted by chemical supplementations and oxygen-tension control. [PDF]
Sci Rep, 2021 Matsumura T +9 more
europepmc +1 more source
Design of Adaptive Tension Control on Tension Reel
, 2019 MasterThe tension reel is a device for winding strips. The outer diameter of the coil increases continuously when the strip is wound. The dynamic characteristics of the tension reel are a time-varying system.
정민진
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source