Results 91 to 100 of about 1,594,117 (300)

Analysis of control stability based on winding characteristics of cylindrical vessels [PDF]

open access: yesJournal of Hebei University of Science and Technology
Aiming at the linear change caused by tension instability in the work of glass fiber winding machine and the instability of tension adjustment in high-speed winding mode, an adaptive fuzzy PID control strategy and a sliding mode control strategy suitable
Kang WANG   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

A study of the effectiveness of various methods of muscular relaxation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

open access: yes, 1979
This study was designed to compare the effectiveness of four different methods of skeletal muscle relaxation. Twenty four male, undergraduate student volunteers were recruited for this study, the age range was 18 to 31 years. The Experiment was conducted
Petersen, Daphne Elaine Leslie
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Kalman-Filter-Based Tension Control Design for Industrial Roll-to-Roll System

open access: yesAlgorithms, 2019
This paper presents a robust and precise tension control method for a roll-to-roll (R2R) system. In R2R processing, robust and precise tension control is very important because improper web tension control leads to deterioration in the quality of web ...
Hyeongjin Hwang   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Homeotic compartment curvature and tension control spatiotemporal folding dynamics. [PDF]

open access: yesNat Commun, 2023
Villedieu A   +6 more
europepmc   +1 more source

Low gravity propellant control using capillary devices in large scale cryogenic vehicles - Related IRAD studies [PDF]

open access: yes
Low gravity propellant control by capillary devices in cryogenic vehicles - screen flow tests, bubble dynamics, residual analysis, settling, and surface tension ...

core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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