Results 101 to 110 of about 1,582,483 (298)

Homeotic compartment curvature and tension control spatiotemporal folding dynamics. [PDF]

open access: yesNat Commun, 2023
Villedieu A   +6 more
europepmc   +1 more source

Spicules and the effect of rigid rods on enclosing membrane tubes

open access: yes, 2005
Membrane tubes (spicules) arise in cells, or artificial membranes, in the nonlinear deformation regime due to, e.g. the growth of microtubules, actin filaments or sickle hemoglobin fibers towards a membrane.
B. Alberts   +10 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Spinarc gas tungsten arc torch holder [PDF]

open access: yes, 1970
Semiautomatic welding torch enables operator to control arc length, torch angle, and spring tension when welding small diameter aluminum tubing. Tungsten is preset for the weld to make arc initiation easier and to eliminate searching for the joint ...
Brace, D. F., Crockett, J. L.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A Flatness-Based Nonlinear Control Scheme for Wire Tension Control of Hoisting Systems

open access: yesIEEE Access, 2019
A double-rope winding hoisting system (DRWHS) is usually employed to transport weight or workers in mines usually from ultra-deep underground (>1000m).
Wanshun Zang   +5 more
doaj   +1 more source

Crystal cleaving machine [PDF]

open access: yes, 1982
A machine is disclosed for cleaving hard crystals. A typical example of which is lithium fluoride, with prcision and uniformity and includes vertical axis positioning control means for an adjustable spring tension guided hammer mechanism employed to ...
Benedicto, J. S. J., Hallberg, F. C.
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multi-Span Tension Control for Printing Systems in Gravure Printed Electronic Equipment

open access: yesApplied Sciences
The tension system is one of the most critical systems in gravure printed electronic equipment. It possesses a complex structure that spans the entire feeding process, from unwinding through printing to rewinding.
Kui He   +4 more
doaj   +1 more source

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