Results 101 to 110 of about 8,976 (260)

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

open access: yesAdvanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka   +9 more
wiley   +1 more source

On one generalization of skew tent maps

open access: yes, 2018
We generalize in this work the properties of the conjugacy of skew tent maps. It is known that the conjugacy $h$ from a skew tent map $g_1$ to $g_2$ is differentiable at a point $x^*$ if and only if there exists left and right limits $\lim\limits_{n\rightarrow \infty}h_n'(x^*-)$ and $\lim\limits_{n\rightarrow \infty}h_n'(x^*+)$, where $h_n$ is a ...
openaire   +2 more sources

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

open access: yesAdvanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini   +8 more
wiley   +1 more source

Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries

open access: yesAdvanced Science, EarlyView.
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao   +5 more
wiley   +1 more source

HL-CAIoT: Hybrid Lightweight Cipher for IoT With Chaotic Maps and Cellular Automata

open access: yesIEEE Access
The growing use of sensory devices in the IoT industry has increased the demand for secure and efficient encryption. Most traditional algorithms are too complex to be applied in IoT systems due to the limited resources available. Based on this, the paper
Biswarup Yogi   +2 more
doaj   +1 more source

A LDH‐Based Supramolecular Photosensitizer‐Functionalized Bioactive Glass Scaffold for Integrated Postoperative Osteosarcoma Recurrence Prevention and Bone Regeneration

open access: yesAdvanced Science, EarlyView.
An intercalation assembly strategy is proposed to construct a novel LDH‐based supramolecular photosensitizer, which exhibits outstanding reactive oxygen species generation activity under 1270 nm laser irradiation. The deposition of supramolecular photosensitizer onto the surface of bioactive glass scaffolds results in the development of an innovative ...
Tao Wang   +9 more
wiley   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou   +7 more
wiley   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng   +6 more
wiley   +1 more source

KDM2B‐Related Neurodevelopmental Disorder A Case‐Series Supporting the CxxC Domain Phenotype With Emphasis on Ocular and Dermatologic Features

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes   +3 more
wiley   +1 more source

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