Results 41 to 50 of about 14,196 (185)

The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming

open access: yesCells, 2023
The induction of pluripotency by enforced expression of different sets of genes in somatic cells has been achieved with reprogramming technologies first described by Yamanaka’s group.
Gracia Mendoza   +11 more
doaj   +1 more source

A terapia gênica e os princípios éticos [PDF]

open access: yes, 2003
Gene therapy is a form of genetic manipulation which tries to correct or to diminish the effects caused by genetic diseases. There are great hopes for the development of this type of therapy, specially for somatic genetic diseases that has no cure, but ...
Rodríguez Yunta, Eduardo
core   +1 more source

Sex hormone deprivation abolishes sex‐specific differences in murine colon inflammation and related lipid mediator production

open access: yesThe FASEB Journal, Volume 38, Issue 14, 31 July 2024.
Female mice exhibit a lower susceptibility to develop colitis compared to male mice, which coincides with higher colonic levels of pro‐resolving EPA and DHA metabolomes, especially 12−/15‐lipoxygenase products in females during the resolving phase and that this is influenced by sex hormones.
Simona Pace   +15 more
wiley   +1 more source

N-acetyl cysteine prevents alterations generated during experimental liver steatosis induced by a chronic consumption of alcohol plus a hypercaloric diet.

open access: yesAnnals of Hepatology
Introduction and Objectives: : Metabolic alterations and alcohol consumption are the most common etiological agents related to hepatic steatosis (HS) development.
Marina Galicia-Moreno   +6 more
doaj   +1 more source

Enfermedad granulomatosa crónica: análisis y abordaje terapéutico [PDF]

open access: yes, 2017
La Enfermedad Granulomatosa Crónica es una enfermedad de carácter genético cuyo diagnóstico tiene lugar en la edad infantil y sus síntomas principales son infecciones severas y recurrentes junto con inflamación que afectan a órganos importantes.
Merayo Pastor, Carlota
core  

Vetores não virais com aplicação na terapia génica: os poliplexos [PDF]

open access: yes, 2016
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraA terapia génica representa uma grande promessa no tratamento de doenças inatas
Loureiro, Ana Patrícia Cardoso
core  

Evaluation of an Antisense Oligonucleotide Targeting CAG Repeats: A Patient-Customized Therapy Study for Huntington’s Disease

open access: yesLife
Huntington’s disease is a genetic disorder characterized by progressive neuronal cell damage in some areas of the brain; symptoms are commonly associated with chorea, rigidity and dystonia.
Sergio Adrian Ocampo-Ortega   +10 more
doaj   +1 more source

Nuevas terapias para la neuropatía óptica hereditaria de Leber [PDF]

open access: yes, 2016
La neuropatía óptica hereditaria de Leber es una enfermedad rara ligada al ADN mitocondrial, de manera que es transmitida verticalmente de madres a hijos.
Lora Domínguez, Paula Carla
core  

Ueg Week 2020 Poster Presentations

open access: yes, 2020
United European Gastroenterology Journal, Volume 8, Issue S8, Page 144-887, October 2020.
wiley   +1 more source

Methyl-group donor supplementation beneficial effects on metabolic, histological, and inflammatory parameters in a murine model of alcoholic steatohepatitis

open access: yesAnnals of Hepatology
Introduction and Objectives: Chronic alcohol consumption is the main cause of alcohol-related liver disease (ARLD) ranging a spectrum characterized by inflammation and progressive fibrosis.
Carolina Diaz-Canul   +5 more
doaj   +1 more source

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