Terapia génica - Open Access .click

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Pirfenidone induces translocation of sirt1 to nucleus and deacetylation of histone 3 slows down the development of fibrosis and tumorigenicity in a experimental model of hepatocarcinoma.

Annals of Hepatology
Introduction and objectives: Hepatocellular carcinoma (HCC) is the most common liver neoplasm worldwide. Pro-inflammatory and pro-fibrogenic processes are key in tumor development.
Hugo C. Monroy-Ramírez +4 more
doaj +1 more source

Terapia gênica

Clinical and Biomedical Research, 2022
A terapia gênica está baseada no conceito de que uma doença genética pode ser corrigida pela substituição ou adição do gene defeituoso. Muita expectativa foi gerada pelos primeiros protocolos, mas o surgimento de complicações inesperadas levou a uma ...
Cláudia D. da Silva +2 more
doaj

Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials

Chemistry – A European Journal, Volume 31, Issue 54, September 24, 2025.
Coacervate vesicles are emerging protocells that merge coacervates’ functionality within membranised architectures. Their diverse formation mechanisms from coacervate droplets yield tunable, responsive systems with broad potential, from synthetic biology to smart materials, offering a powerful, programmable platform for next‐generation bioinspired ...
Francesco Vicentini, Federica Battistin, Pierangelo Gobbo +2 more
wiley +1 more source

Terapia génica en la distrofia muscular de Duchenne [Fernández Fuertes] [PDF]

, 2021
La distrofia muscular de Duchenne es un trastorno genético grave y degenerativo que se diagnostica durante la infancia y provoca debilidad muscular progresiva, además de complicaciones respiratorias y cardiacas.
Férnandez Fuertes, María
core

Pirfenidone slows the development of fibrosis and malignant neoplasms by modulating inflammation in an experimental model of hepatocarcinoma.

Annals of Hepatology
Introduction and objectives: Hepatocellular carcinoma (HCC) is the most common liver neoplasm in the world. Inflammatory, oxidative and fibrogenic processes are key in tumor development and propagation.
Scarlet Arceo-Orozco +4 more
doaj +1 more source

Terapias avanzadas en enfermedades raras

Arbor: Ciencia, Pensamiento y Cultura, 2018
Las terapias avanzadas comprenden un grupo de medicamentos biológicos basados en la terapia génica, la terapia celular y la ingeniería de tejidos. En este artículo se presentan algunos conceptos básicos, se describen las estrategias más prometedoras y se
Cristina Fillat +3 more
doaj +1 more source

Terapia génica [PDF]

, 1998
The lecture was an introduction to gene therapy. The integrative mechanisms underlying homeostasis in complex organisms are based on the cell-specific gene expression.
Vargas, A. M.
core +1 more source

Detección de la mutación E8SJM en el gen LIPA, por PCR en tiempo real, para la investigación de la enfermedad por almacenamiento de ésteres de colesterol

Anales de la Facultad de Medicina, 2018
Introducción: La enfermedad por Almacenamiento de Ésteres de Colesterol (CESD; Cholesteryl Ester Storage Disease) es una enfermedad de depósito lisosomal, su presentación es bastante variable y su diagnóstico constituye un desafío.
Diana Rojas Málaga +3 more
doaj +1 more source

N-acetyl cysteine prevents alterations generated during experimental liver steatosis induced by a chronic consumption of alcohol plus a hypercaloric diet.

Annals of Hepatology
Introduction and Objectives: : Metabolic alterations and alcohol consumption are the most common etiological agents related to hepatic steatosis (HS) development.
Marina Galicia-Moreno +6 more
doaj +1 more source

The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming

Cells, 2023
The induction of pluripotency by enforced expression of different sets of genes in somatic cells has been achieved with reprogramming technologies first described by Yamanaka’s group.
Gracia Mendoza +11 more
doaj +1 more source

specialties of internal medicine
gene therapy