Results 21 to 30 of about 236,465 (163)
Journal of Clinical Laboratory Analysis, Volume 35, Issue 11, November 2021., 2021 Summary of key results from this study. (1) “Linkage disequilibrium was identified between ‐173 G>C and STR‐794 CATT5‐8 polymorphisms (D′ value = 0.62, r2 = 0.17, p < 0.001, Figure 1). (2) “the ‐173 CC genotype was associated with high MIF serum levels ".
Jorge Hernández‐Bello +7 more
wiley +1 more source
Traffic light at DSB-transit regulation between gene transcription and DNA repair. [PDF]
FEBS LettUpon the generation of a break, DNA damage response activation represses transcription of genes in cis via an ATM‐ and PRC1‐dependent chromatin modification and compaction. Concomitantly, RNAPII accumulates in proximity to DNA ends and locally synthesizes chromatin‐bound ncRNAs.
Modafferi S +4 more
europepmc +2 more sources
Terapia génica en el manejo de las distrofias retinianas
, 2018 La terapia génica se define como los procedimientos de transferencia de material genético a órganos específicos, con el propósito de producir efectos terapéuticos para así corregir defectos o enfermedades genéticas, ya sea de forma directa (in vivo) o ...
Hernández, Luz Ángela +2 more
core +3 more sources
Terapia génica contra el cáncer: Una nueva era antineoplásica [PDF]
, 2021 El cáncer sigue siendo una de las principales causas de mortalidad a nivel mundial, detrás de las enfermedades cardiovasculares. Factores genéticos y epigenéticos están asociados al riesgo de contraer la enfermedad.
Sepúlveda López, Isabel
core +1 more source
El gen como medicamento: terapia génica [PDF]
, 2013 Entendemos terapia génica como la introducción de material genético con ca- pacidad de expresar la versión correcta de una proteína en células donde el gen es defi- ciente.
Segovia Sanz, José Carlos
core +1 more source
Differential Expression and PAH Degradation: What Burkholderia vietnamiensis G4 Can Tell Us?
International Journal of Microbiology, Volume 2020, Issue 1, 2020., 2020 Petroleum is the major energy matrix in the world whose refining generates chemical byproducts that may damage the environment. Among such waste, polycyclic aromatic hydrocarbons (PAH) are considered persistent pollutants. Sixteen of these are considered priority for remediation, and among them is benzo(a)pyrene.
Guilherme Pinto Cauduro +5 more
wiley +1 more source
TERAPIA GÉNICA Y PRINCIPIOS ÉTICOS
, 2003 La terapia génica constituye una forma de manipulación genética que trata de corregir o disminuir los efectos que ocasionan enfermedades de origen genético. Existen grandes esperanzas en el desarrollo de este tipo de terapia, sobre todo para enfermedades
Rodríguez Yunta,Eduardo
core +1 more source
Neuropilin-1: A Conserved Entry Receptor for SARS-CoV-2 and a Potential Therapeutic Target
BiomedicinesBackground/Objectives: Neuropilin-1 (NRP1) is a key co-receptor for SARS-CoV-2, complementing the ACE2 receptor. Several investigations have documented highly conserved sequences in this receptor, supporting the implication of NRP1 as a key mediator in ...
Vivany Maydel Sierra-Sánchez +9 more
doaj +1 more source
Princípios de terapia génica [PDF]
, 2016 Podríamos definir la terapia génica como la introducción de un gen foráneo en el ser humano con fines terapéuticos. La terapia génica comenzó a ser utilizada en el ser humano a principios de los años 90 y en los últimos años ha empezado a dar sus frutos.
Reverter Velasco, Naiara
core
Biomolecular Corona of Extracellular Vesicles: Report on Isev Workshop
Journal of Extracellular Biology, Volume 5, Issue 8, August 2026.ABSTRACT The concept of the “biomolecular corona” (BC) was first introduced to describe the spontaneous absorption of molecules, mainly proteins, onto the surface of synthetic nanoparticles upon exposure to biological fluids. More recently, the same term has been used to describe biomolecules that dynamically interact with the surface of extracellular ...
Lucia Paolini +51 more
wiley +1 more source