Results 1 to 10 of about 14,196 (185)

AAV-HDV: An Attractive Platform for the In Vivo Study of HDV Biology and the Mechanism of Disease Pathogenesis

open access: yesViruses, 2021
Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis, but little is known about the molecular mechanisms involved. We have recently developed an HDV mouse model based on the delivery of HDV replication-competent genomes ...
Sheila Maestro   +8 more
doaj   +1 more source

EFFECT OF SUPPLEMENTATION WITH TYPICAL MEXICAN FOODS (OPTUNA FICUS INDICA, THEOBROMA CACAO AND EDIBLE CRICKETS) IN HIGH-FAT/HIGH-SUGAR DIET-FED MICE

open access: yesAnnals of Hepatology, 2022
Introduction and objectives: The obesogenic environment, including high fat/ high sugar diet, are risk factors for developing multiple diseases associated with obesity, such as metabolic-associated fatty liver disease (MAFLD) and metabolic syndrome ...
R. Rosas Campos   +5 more
doaj   +1 more source

Moringa oleifera decreases biomarkers of oxidative stress in a murine NASH model

open access: yesAnnals of Hepatology, 2022
Introduction and Objectives: This study aimed to evaluate the effect of Moringa oleifera aqueous extract on biomarkers of oxidative stress in a murine model of NASH. Material and Methods: The characterization of the extract was performed by DPPH and ABTS
A Monraz-Méndez   +6 more
doaj   +1 more source

terapia génica en México y España, una aproximación bioética desde la investigación científica

open access: yesRevista de Bioética y Derecho, 2021
La terapia génica es una línea de investigación que, por medio de la transferencia genética, busca nuevos tratamientos a enfermedades que son difíciles de tratar mediante métodos tradicionales.
Alvaro Olivo Yepez   +3 more
doaj   +1 more source

Targeted Expression to Liver of an antimiR-33 Sponge as a Gene Therapy Strategy against Hypercholesterolemia: In Vitro Study

open access: yesCurrent Issues in Molecular Biology, 2023
Atherosclerosis is the leading cause of cardiovascular diseases in Mexico and worldwide. The membrane transporters ABCA1 and ABCG1 are involved in the reverse transport of cholesterol and stimulate the HDL synthesis in hepatocytes, therefore the ...
Mariela Montaño-Samaniego   +7 more
doaj   +1 more source

Strategies for Targeting Gene Therapy in Cancer Cells With Tumor-Specific Promoters

open access: yesFrontiers in Oncology, 2020
Cancer is the second cause of death worldwide, surpassed only by cardiovascular diseases, due to the lack of early diagnosis, and high relapse rate after conventional therapies.
Mariela Montaño-Samaniego   +4 more
doaj   +1 more source

Oxidative and Fibrinolytic Mechanisms: Two Important Processes to Consider in Platelet Storage

open access: yesTurkish Journal of Hematology, 2023
Objective: Platelet-rich plasma (PRP) is used in multiple coagulation disorders. Its therapeutic effectiveness relies on technical procedures related to PRP procurement and preservation because free radicals induce platelet activation and aging.
Jesus Javier Garcia-Bañuelos   +6 more
doaj   +1 more source

Fluorescence-Linked Aptamer Assay for SARS-CoV-2 Spike-Protein: A Step-by-Step Performance Analysis in Clinical Samples

open access: yesDiagnostics, 2022
The COVID-19 pandemic has been a main concern over the last two years and has become one of the most important crises in the history of human health. Today, there is still a need for affordable and reliable diagnostic tests for massive disease monitoring.
Pablo Alberto Franco-Urquijo   +8 more
doaj   +1 more source

Terapia génica: ¿Qué es y para qué sirve? [PDF]

open access: yes, 2005
Gene therapy has developed as a method of approach to the treatment of human diseases based on the transfer of genetic material to the cells of an individual.
Ruiz-Castellanos, M. (M.)   +1 more
core   +1 more source

Biotecnología y sociedad: conflicto, desarrollo y regulación [PDF]

open access: yes, 1993
Publicado en Arbor, 585: 9-47, 1994.[EN] Some of the major issues related to the development of contemporary biotechnology/genetic engineering are analysed in this Working Paper.
Luján, José Luis, Moreno, Luis
core   +1 more source

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