Results 241 to 250 of about 6,483 (296)
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Teratology, 1982
AbstractPregnant rats and mice received high doses of cocaine hydrochloride by intraperitoneal injection. Despite treatment periods which included most of organogenesis, no increase in congenital abnormalities was observed. Rats showed significant reductions in maternal and fetal weights as well as increased resorption frequencies. Fetal edema was also
A G, Fantel, B J, Macphail
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AbstractPregnant rats and mice received high doses of cocaine hydrochloride by intraperitoneal injection. Despite treatment periods which included most of organogenesis, no increase in congenital abnormalities was observed. Rats showed significant reductions in maternal and fetal weights as well as increased resorption frequencies. Fetal edema was also
A G, Fantel, B J, Macphail
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, 2008 New England Journal of Medicine, 1986
In 1981, Katie Laurel Wells was born with a cleft lip, an optic-nerve defect, and limb abnormalities, including absence of the left arm.
J L, Mills, D, Alexander
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In 1981, Katie Laurel Wells was born with a cleft lip, an optic-nerve defect, and limb abnormalities, including absence of the left arm.
J L, Mills, D, Alexander
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Annual Review of Nutrition, 1995
Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
D R, Soprano, K J, Soprano
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Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
D R, Soprano, K J, Soprano
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Journal of Animal Science, 1984
Many compounds synthesized by plants are known to be teratogenic in laboratory animals, but only a few have been shown by feeding trials to produce terata in livestock. Studies of plant teratogens affecting livestock have not moved forward in a systematic nor rapid way because of the logistical problems connected with such experiments in large animals.
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Many compounds synthesized by plants are known to be teratogenic in laboratory animals, but only a few have been shown by feeding trials to produce terata in livestock. Studies of plant teratogens affecting livestock have not moved forward in a systematic nor rapid way because of the logistical problems connected with such experiments in large animals.
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Annals of Internal Medicine, 1979
Excerpt To the editor: The excellent and valuable review in the June issue by Drs. Spark and Dickstein, "Bromocriptine and Endocrine Disorders" (1), referred to the potential teratogenicity of this...
R L, Elton, H M, Langrall
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Excerpt To the editor: The excellent and valuable review in the June issue by Drs. Spark and Dickstein, "Bromocriptine and Endocrine Disorders" (1), referred to the potential teratogenicity of this...
R L, Elton, H M, Langrall
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2011
AbstractA consideration of teratogenic exposures includes not only an agent (chemical, radiation, biologic) but an exposure level and timing of exposure. There are criteria by which exposures are evaluated for a causal connection with an abnormal outcome.
Sarah, Običan, Anthony R, Scialli
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AbstractA consideration of teratogenic exposures includes not only an agent (chemical, radiation, biologic) but an exposure level and timing of exposure. There are criteria by which exposures are evaluated for a causal connection with an abnormal outcome.
Sarah, Običan, Anthony R, Scialli
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Journal of Psychopharmacology, 1992
Animal tests for teratogenicity of drugs have more medicolegal and political significance than relevance to human therapeutics. Test conditions differ widely from human therapeutic regimens and major species differences are common. Occasionally the tests will define a drug or group of drugs with an unpleasant potential, and sometimes a mode of action ...
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Animal tests for teratogenicity of drugs have more medicolegal and political significance than relevance to human therapeutics. Test conditions differ widely from human therapeutic regimens and major species differences are common. Occasionally the tests will define a drug or group of drugs with an unpleasant potential, and sometimes a mode of action ...
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Teratogen update: Iodine deficiency, a community teratogen
Teratology, 1997In the last decade, iodine deficiency disorders (IDD) have become recognized as the most common preventable cause of mental retardation worldwide. Iodine deficiency interferes severely with prenatal and postnatal growth and neurologic development of individuals.
J G, Hollowell, W H, Hannon
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