Results 271 to 280 of about 17,298 (331)
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Clinics in Perinatology, 2014
In utero exposure to certain drugs early in pregnancy may adversely affect nephrogenesis. Exposure to drugs later in pregnancy may affect the renin-angiotensin system, which could have an impact on fetal or neonatal renal function. Reduction in nephron number and renal function could have adverse consequences for the child several years later. Data are
Thomas M, Morgan+2 more
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In utero exposure to certain drugs early in pregnancy may adversely affect nephrogenesis. Exposure to drugs later in pregnancy may affect the renin-angiotensin system, which could have an impact on fetal or neonatal renal function. Reduction in nephron number and renal function could have adverse consequences for the child several years later. Data are
Thomas M, Morgan+2 more
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Is Bendectin a Teratogen? [PDF]
We studied the first-trimester exposure to Bendectin for several major categories of birth defects among infants ascertained through the Metropolitan Atlanta Congenital Defects Program from 1968 to 1978. No associations were found between any of these defect categories and Bendectin exposure.
Levy M. James+3 more
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The role of teratogens in neural crest development
Birth Defects Research, 2020The neural crest (NC), discovered by Wilhelm His 150 years ago, gives rise to a multipotent migratory embryonic cell population that generates a remarkably diverse and important array of cell types during the development of the vertebrate embryo.
Santiago Cerrizuela+2 more
semanticscholar +1 more source
The SAGE Encyclopedia of Human Communication Sciences and Disorders, 2017
Teratogens are substances that may produce physical or functional defects in the human embryo or fetus [3] after the pregnant woman is exposed to the substance. Alcohol and cocaine are examples of such substances.
E. Pereira, J. Samanich, R. Marion
semanticscholar +1 more source
Teratogens are substances that may produce physical or functional defects in the human embryo or fetus [3] after the pregnant woman is exposed to the substance. Alcohol and cocaine are examples of such substances.
E. Pereira, J. Samanich, R. Marion
semanticscholar +1 more source
Reflections on the etiology of structural birth defects: Established teratogens and risk factors.
Birth defects research. Clinical and molecular teratology, 2015BACKGROUND Various experts in clinical teratology have proposed what they consider to be well-established teratogens. With the recent growth in the number of resources and investigations, there has been a notable proliferation of proposed risk factors as
M. Feldkamp, L. Botto, J. Carey
semanticscholar +1 more source
Teratogen update: Iodine deficiency, a community teratogen
Teratology, 1997In the last decade, iodine deficiency disorders (IDD) have become recognized as the most common preventable cause of mental retardation worldwide. Iodine deficiency interferes severely with prenatal and postnatal growth and neurologic development of individuals.
W. Harry Hannon, Joseph G. Hollowell
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Epidemiology of major congenital malformations with specific focus on teratogens.
Current Drug Safety, 2013BACKGROUND Major congenital malformations (MCMs) are a significant cause of infant morbidity and mortality and constitute an important societal and economic burden.
S. Chaabane, A. Bérard
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American Journal of Industrial Medicine, 1983
Reproduction can be impaired in animals and man by drugs and various environmental agents. Depending on the time of exposure—from fertilization through the fetal period and eventually during lactation—the consequences can range from embryotoxicity, gross malformations and a large variety of more subtle morphological, biochemical, and functional ...
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Reproduction can be impaired in animals and man by drugs and various environmental agents. Depending on the time of exposure—from fertilization through the fetal period and eventually during lactation—the consequences can range from embryotoxicity, gross malformations and a large variety of more subtle morphological, biochemical, and functional ...
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Cancer chemotherapeutic agents as human teratogens.
Birth defects research. Clinical and molecular teratology, 2012BACKGROUND Cancer is the second leading cause of death among women of reproductive age. Although the coincidence of pregnancy and cancer is rare and treatment may sometimes be safely delayed, the use of chemotherapeutic agents in pregnancy is sometimes ...
Brady P. Selig+8 more
semanticscholar +1 more source
2011
Teratology, the study of birth and developmental anomalies, has been a descriptive science based on detection of birth defects by clinical or laboratory methods. Animal test systems commonly employed have shown modest to excellent success in identifying chemical teratogens. With the advent of epigenetic study of the developmental process, prevention of
Vincent F. Garry, Peter Truran
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Teratology, the study of birth and developmental anomalies, has been a descriptive science based on detection of birth defects by clinical or laboratory methods. Animal test systems commonly employed have shown modest to excellent success in identifying chemical teratogens. With the advent of epigenetic study of the developmental process, prevention of
Vincent F. Garry, Peter Truran
openaire +3 more sources