Results 291 to 300 of about 17,298 (331)
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Journal of Psychopharmacology, 1992
Animal tests for teratogenicity of drugs have more medicolegal and political significance than relevance to human therapeutics. Test conditions differ widely from human therapeutic regimens and major species differences are common. Occasionally the tests will define a drug or group of drugs with an unpleasant potential, and sometimes a mode of action ...
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Animal tests for teratogenicity of drugs have more medicolegal and political significance than relevance to human therapeutics. Test conditions differ widely from human therapeutic regimens and major species differences are common. Occasionally the tests will define a drug or group of drugs with an unpleasant potential, and sometimes a mode of action ...
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Clinical Obstetrics and Gynecology, 1975
There is nothing unique about rubella viruses or cytomegaloviruses. They are classic teratogens and, in this respect, not only follow but exemplify most of the principles of human teratology.
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There is nothing unique about rubella viruses or cytomegaloviruses. They are classic teratogens and, in this respect, not only follow but exemplify most of the principles of human teratology.
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Predictive value of minor anomalies: II. Use in cohort studies to identify teratogens.
Teratology, 1987Cohort studies of putative human teratogens can identify the full spectrum of phenotypic effects, including both major malformations and minor anomalies.
Lewis B. Holmes +5 more
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Bipartite axiation follows incomplete epiboly in zebrafish embryos treated with chemical teratogens.
The Journal of experimental zoology, 1984Medial clefts in the axis of the trunk region are malformations known from many chordates and are mostly referred to as rachischisis anterior. In teleosts, rachischisis was previously ascribed either to secondary rifting of a single uniform axial ...
M. Baumann, K. Sander
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Hospital Practice, 1984
In the years since thalidomide, we have added significantly to our list of known teratogens, but we are still unhappily ignorant about the degree of risk and mechanisms of teratogenesis. Thus, the physician faced with the concern of a pregnant patient confronts difficult dilemmas.
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In the years since thalidomide, we have added significantly to our list of known teratogens, but we are still unhappily ignorant about the degree of risk and mechanisms of teratogenesis. Thus, the physician faced with the concern of a pregnant patient confronts difficult dilemmas.
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Whole embryo culture: a screening technique for teratogens?
Teratogenesis, carcinogenesis, and mutagenesis (Print), 1982Head-fold and early somite stages of mouse and rat embryos maintained in whole-embryo culture throughout much of the period of organogenesis demonstrate normal growth and morphogenesis.
T. Sadler, W. Horton, C. W. Warner
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Steroidal Alkaloid Teratogens: Molecular Probes for Investigation of Craniofacial Malformations
, 1996Holoprosencephaly, a malformation sequence that results from impaired midline cleavage of the embryonic forebrain, is expressed as a spectrum of craniofacial anomalies of which cyclopia is the most severe. The Veratrum alkaloids are the most prominent of
William Gaffield, R. Keeler
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Genotoxic and mutagenic studies of teratogens in developing rat and mouse
Drug and chemical toxicology (New York, N.Y. 1978), 2019E. Rencüzoğulları, M. Aydın
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Human teratogens and genetic phenocopies. Understanding pathogenesis through human genes mutation.
European Journal of Medical Genetics, 2017M. Cassina +4 more
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Teratology, 1972
AbstractA review is given of the literature on the supposed causative relation between hypoglycemia and teratogenicity in the origin of malformations due to treatment with insulin and certain sulfonamides. An appendix reports antiteragenic effects of insulin in combination with 3‐acetylpyridine.
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AbstractA review is given of the literature on the supposed causative relation between hypoglycemia and teratogenicity in the origin of malformations due to treatment with insulin and certain sulfonamides. An appendix reports antiteragenic effects of insulin in combination with 3‐acetylpyridine.
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