Results 51 to 60 of about 28,669 (256)

Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]

, 2017
Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
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Uncorrected Tetralogy of Fallot in a 45yr old Man: A case report

Perspectives In Medical Research, 2019
Teratology of Fallot (TOF), congenital heart ...
Chaitanya Y1, Veera Reddy P2
doaj  

Epidemiologic aspects of neural tube defects in South East Iran [PDF]

, 2006
Objectives: To investigate the rate of neural tube defects (NTDs) and their relation to gender, maternal age, consanguineous marriage, season, and drug consumption in Birjand, Iran.
Afshar, M., Farhud, D., Golalipour, M.J.
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Medication use in pregnancy: a cross-sectional, multinational web-based study [PDF]

, 2014
Objectives: Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. his study aimed to examine patterns and factors associated with medications use in pregnancy from a
Bjornsdottir, I., Drozd, M., Gjergja Juraski, R., Hameen-Anttila, K., Juch, H., Kennedy, D., Lupattelli, A., Mardby, A. C., Moretti, M. E., Nordeng, H., Odalovic, M., Panchaud, A., Passier, A., Rieutord, A., Rudolf, G., Spigset, O., Twigg, M. J., Zagorodnikova, K.   +17 more
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Lomitapide: Targeting METTL3 to Overcome Osimertinib Resistance in NSCLC Through Autophagy Activation

MedComm – Oncology, Volume 4, Issue 1, March 2025.
1. Lomitapide can significantly inhibit the methyltransferase activity of METTL3 and reduce the m6A modification and expression of UQCC2. 2. The METTL3/UQCC2 axis inhibition by lomitapide could activate autophagy‐mediated cell death, thus reversing osimertinib resistance in NSCLC cells. ABSTRACT Osimertinib resistance remains a significant challenge in
Xiaohui Du, Congcong Zhang, Ying Li, Peipei He, Jian Wang, Xuena Chen, Han Wang, Qi Wang   +7 more
wiley   +1 more source

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice [PDF]

, 2018
Fractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway contribute to NTDs in humans and mice, but whether this pathway independently determines bone mass is ...
A Kamalakar, A Trinh, AJ Copp, AJ Copp, AS Findlay, B Wang, BA Alman, C Cooper, C Hartmann, CF Davey, CH Chen, D Karasik, D Szklarczyk, DG Winkler, DJ Epstein, DM Juriloff, E Canalis, E Nikolopoulou, EM Curtis, GH Li, GL Galea, GL Galea, GL Galea, GL Galea, H Marreiros, H Yin, HF Zheng, IR Orriss, IR Orriss, JK Morris, JN Murdoch, K Estrada, KC Keller, KS Joeng, L D’Andrea, LJ Martin, LL Yates, LL Yates, M Akbar, M Kalogeropoulos, ME Ross, MJ Anderson, MJ Harris, MJ Harris, MR Dohn, NC Nowlan, P Andre, P Elms, P Ybot-Gonzalez, P Ybot-Gonzalez, R Klootwijk, R Xu, S Babayeva, S Li, S Maere, SA Brown, SE Taylor, SJ Conway, T Dodge, T Yang, UM Ayturk, V Martinelli, W Yang, Y Erdem, Y Koyabu, Y Lei, Z Kibar   +66 more
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Melatonin Alleviates Behavioral and Neurodevelopmental Abnormalities in Offspring Caused by Prenatal Stress

CNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.
Prenatal stress increases the risk of neurodevelopmental disorders and psychiatric illnesses in offspring. This study demonstrates that melatonin alleviates emotional and cognitive deficits in offspring exposed to prenatal stress. By modulating the PI3K/AKT/NF‐κB signaling pathway in microglia and reducing the elevated expression of CXCL10 in the ...
Dong Wu, Jingyi Du, Tiantian Zhao, Naigang Li, Xinghui Qiao, Fan Peng, Dongshuang Wang, Jiaming Shi, Shu Zhang, Can Diao, Liyan Wang, Wenjuan Zhou, Aijun Hao   +12 more
wiley   +1 more source

Safety assessment of the fungal immunomodulatory protein from Ganoderma microsporum (GMI) derived from engineered Pichia pastoris: Genetic toxicology, a 13-week oral gavage toxicity study, and an embryo-fetal developmental toxicity study in Sprague-Dawley rats

Toxicology Reports, 2022
The 12.4 kDa fungal immunomodulatory protein from Ganoderma microsporum (GMI) has bioactivity in vitro and in vivo. This study assessed the safety of GMI derived from engineered Pichia pastoris in Sprague-Dawley rats as a dietary supplement and food ...
Hsu-Yuan Fu, Ruey-Shyang Hseu
doaj  

Newborn English Bulldogs with Multiple Malformation Syndrome and Lethal Characters

Journal of Animal Reproduction and Biotechnology, 2019
A female English bulldog was gave birth two neonates by cesarean section on the sixty one days after mating, but both neonates were died soon after birth.
Si-Jung Jang, Minkyung Kim, Hyeon-Jeong Lee, Young-Sung You, Jaehoon Lee, Sung-Lim Lee   +5 more
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Is there a relationship between prenatal cannabis exposure and the development of aggressive behaviour? [PDF]

, 2019
Treball Final de Grau en Psicologia. Codi: PS1048. Curs: 2018/2019.Numerous studies focusing on the effects of cannabis use at the psychobiological level have shown cognitive impairment as well as memory and attention deficits.
Castro Valera, Iván José
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