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Terlipressin-induced hyponatremic seizure

Scandinavian Journal of Gastroenterology, 2010
Terlipressin is a splanchnic constrictor that is used to control variceal bleeding and is considered to have a very good safety profile compared to vasopressin. However, side effects such as hyponatremia and seizure, although very rare, can occur. Recently, the authors have experienced a case of hyponatremia induced by infusion of terlipressin which ...
Soon Ho Um   +9 more
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Terlipressin-induced ventricular arrhythmia

Scandinavian Journal of Gastroenterology, 2008
During intravenous treatment with terlipressin for recurrent gastrointestinal (GI) bleeding, a 50-year-old male with no history of heart disease developed a newly prolonged QT interval and torsade de pointes. Risk factors present for acquired long QT syndrome were mineral dysbalance and a history of alcohol abuse with hepatic impairment.
Karel Urbánek   +3 more
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Hyponatraemia during terlipressin therapy

Gut, 2010
We have read with interest the study by Lo et al 1 in a recent issue of Gut . Apart from the findings that short-term therapy with terlipressin in combination with ligation seems to improve outcome in bleeding oesophageal varices (BOVs) compared to longer treatment with terlipressin, a shorter treatment period with terlipressin most likely reduces the ...
Krag, Aleksander   +3 more
openaire   +4 more sources

Formulary Drug Reviews: Terlipressin

Hospital Pharmacy, 2023
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing
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Terlipressin (Terlivaz) for Hepatorenal Syndrome

The Medical Letter on Drugs and Therapeutics, 2023
The FDA has approved the intravenously administered synthetic vasopressin analog terlipressin (Terlivaz – Mallinckrodt) to improve kidney function in adults with hepatorenal syndrome (HRS) and a rapid decline in kidney function. Terlipressin is the first drug to be approved for this indication in the US; it has been available in Europe and elsewhere ...
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IMPACT OF TERLIPRESSIN ON RENAL GRAFT FUNCTION

Shock, 2008
To assess the effect of a bolus of terlipressin in brain-dead donors with shock refractory to norepinephrine, a retrospective study was conducted in a 16-bed intensive care unit of a university hospital. Twenty brain-dead donors were treated with norepinephrine within the study period.
A. Geissler   +5 more
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The use of terlipressin in hepatorenal syndrome

Dialysis & Transplantation, 2010
AbstractHepatorenal syndrome (HRS) is a potentially reversible cause of acute renal failure that occurs in patients with hepatic failure resulting from advanced cirrhosis. It is characterized by impaired kidney function in the setting of normal renal parenchyma, alterations in cardiovascular function, splanchnic vasodilation, and overactivity of the ...
Inna Rozov‐Ung, Mandip Panesar
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Terlipressin for hepatorenal syndrome

Current Opinion in Gastroenterology
Purpose of review The definition and diagnostic criteria of hepatorenal syndrome-acute kidney injury (HRS-AKI) has undergone recent changes. A major vasoconstrictor, terlipressin, has recently been approved as pharmacotherapy for HRS-AKI in the United States.
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Preparation and characterization of PEGylated terlipressin

Journal of Applied Polymer Science, 2010
AbstractTerlipressin was chemically modified by reaction with succinimidyl propionate‐ monomethoxy polyethylene glycol (mPEG‐SPA). To determine the PEGylated degree, the position and the optimized condition for PEGylated terlipressin, the reactions were monitored in different pH value buffers at different molar ratios by reversed‐phase high performance
Hansen Lin   +3 more
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[The role of terlipressin in hepatorenal syndrome].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2010
Hepatorenal syndrome (HRS) is a severe complication in patients with endstage liver disease. It consists of functional renal vasoconstriction leading to severe reduction of the glomerular filtration rate. In some patients the renal failure shows a rapidly progressive course, a clinical pattern known as type 1 HRS.
FORCELLINI, Silvia, FABBIAN, Fabio
openaire   +2 more sources

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