Results 111 to 120 of about 17,339,935 (305)
Long Term Variability of SDSS Quasars
, 2003 We use a sample of 3791 quasars from the Sloan Digital Sky Survey (SDSS) Early Data Release (EDR), and compare their photometry to historic plate material for the same set of quasars in order to study their variability properties.
Aretxaga I. +9 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Understanding Czech Long-Term Unemployment [PDF]
, 2002 daniel.munich@cerge-ei.czOne potential impact of the looming EU accession of Central European economies is unemployment hysteresis working through long-term unemployment (LTU).
Jurajda, Stepan, Münich, Daniel
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
DiagnosticsHypoglycemia is a common metabolic disorder that occurs in the neonatal period. Early identification of neonates at risk of developing hypoglycemia can optimize therapeutic strategies in neonatal care.
Lin-Yu Wang +5 more
doaj +1 more source
Board Diversity by Term Limits? [PDF]
, 2019 Four-fifths of the corporate board seats in the United States are held by men and a shocking number of companies lack any female representation on their boards.
Nili, Yaron, Rosenblum, Darren
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Trends In Long-term Unemployment [PDF]
, 2015 Long-term unemployment reached historically high levels following the Great Recession of 2007–2009. Both the number and share of the unemployed who are long-term unemployed typically continue to increase after a recession ends, before falling during a ...
Kosanovich, Karen +1 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source