Results 161 to 170 of about 33,047,881 (379)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

The time validity of Philip's two‐term infiltration equation: An elusive theoretical quantity?

open access: yesVadose Zone Journal
The two‐term infiltration equation I(t)=St+At is commonly used to determine the sorptivity, S (LT−1/2), and product, A=cKs (LT−1), of the dimensionless multiple c and saturated soil hydraulic conductivity Ks (LT−1) from cumulative vertical infiltration ...
Jasper A. Vrugt   +5 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Short-term effects of air pollution on health: a European approach using epidemiological time-series data. The APHEA project: background, objectives, design [PDF]

open access: bronze, 1995
Klea Katsouyanni   +10 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Short-Term Forecasting of Non-Stationary Time Series

open access: yesEngineering Proceedings
Forecasting climate events is crucial for mitigating and managing risks related to climate change; however, the problem of non-stationarity in time series (NTS) arises, making it difficult to capture and model the underlying trends.
Amir Aieb   +3 more
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Identification of an unknown source term for a time fractional fourth-order parabolic equation

open access: yesElectronic Journal of Differential Equations, 2016
In this article, we considered two inverse source problems for fourth-order parabolic differential equation with fractional derivative in time. Determination of a space dependent source term from the data given at some time t=T is considered in one ...
Sara Aziz, Salman A. Malik
doaj  

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