Results 61 to 70 of about 4,280,482 (303)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Energy density and weight change in a long-term weight-loss trial [PDF]

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2008
Identifying dietary factors that contribute to weight loss is an important task given the health risks linked to obesity and the difficulty in achieving weight loss among obese individuals. This study examined the effect of lowered energy density on weight loss. Subjects were 213 men and women with BMI of 30–39 kg/m
Welsh Ericka M   +9 more
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Concept-based one-class SVM classifier with supervised term weighting scheme for imbalanced sentiment classification

open access: yesEngineering and Applied Science Research, 2021
Imbalanced sentiment is one of the key classification issues. Many studies have proposed imbalanced sentiment classification improvements, but the topic remains problematic as a major challenge.
Khanista Namee, Jantima Polpinij
doaj  

Supervised term weighting for automated text categorization [PDF]

open access: yesProceedings of the 2003 ACM symposium on Applied computing, 2003
The construction of a text classi.er usually involves (i) a phase of term selection, in which the most relevant terms for the classi.cation task are identi.ed, (ii) a phase of term weighting, in which document weights for the selected terms are computed, and (iii) a phase of classi.er learning, in which a classi.er is generated from the weighted ...
Debole F, Sebastiani F
openaire   +7 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Bento and Buffet: Two Approaches to Flexible Summative Assessment

open access: yesCollected Essays on Learning and Teaching, 2016
This practice-sharing piece outlines two main approaches to flexible summative assessment schemes, including for each approach one example from my practice and another from a published study. The bento approach offers the same assessments to all students
Nicky Didicher
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Retrieval of source documents in a text reuse system

open access: yesJurnal Teknologi dan Sistem Komputer, 2020
The architecture of the text-reuse detection system consists of three main modules, i.e., source retrieval, text analysis, and knowledge-based postprocessing. Each module plays an important role in the accuracy rate of the detection outputs.
Nathaniel Clarence Haryanto   +2 more
doaj   +1 more source

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