Results 81 to 90 of about 4,280,482 (303)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Term weighting is an essential part of the modern information retrieval systems. Out of the three main components of a term weighting strategy --- term frequency, inverse document frequency, and document length normalization --- the term frequency factor
Singhal, Amitabh
core +6 more sources
Weighting factors of sire daughter information in international genetic evaluations [PDF]
International genetic evaluations of dairy bulls are currently based on national genetic evaluation results. Total number of daughters in a country is used to weight national information, but may not optimally reflect the precision of a sire's daughter ...
Fikse, WF, Banos, G
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Pengembangan Sistem Penelusuran Katalog Perpustakaan Dengan Metode Rocchio Relevance Feedback
Tanpa adanya sistem penelusuran katalog yang terkomputerisasi maka pengunjung perpustakaan mengalami kesulitan untuk mengetahui ketersediaan bahan pustaka dan pustakawan mengalami kesulitan dalam mengelola bahan pustaka.
Pausta Yugianus +2 more
doaj +1 more source
The importance of Term Weighting in semantic understanding of text: A review of techniques. [PDF]
Rathi RN, Mustafi A.
europepmc +1 more source
A Note on the Relation of Weighting and Matching Estimators [PDF]
This paper compares the inverse-probability-of-selection-weighting estimation principle with the matching principle and derives conditions for weighting and matching to identify the same and the true distribution, respectively.
Michael Lechner
core
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source

