Results 91 to 100 of about 8,969 (257)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 1997 Term weighting is an essential part of the modern information retrieval systems. Out of the three main components of a term weighting strategy --- term frequency, inverse document frequency, and document length normalization --- the term frequency factor
Singhal, Amitabh
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The impact of term weighting method on Twitter sentiment analysis
, 2018 Term weighting is an important step which has direct impact on the result in classical text classification. However, the behavior of the term weighting method may vary depending on different preprocessing techniques in sentiment analysis which considered
Tümüklü Özyer, Gülşah +3 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Analisis Performansi Term Weighting dengan Metode Supervised Term Weighting untuk Kategorisasi Teks [PDF]
, 2012 ABSTRAKSI: Kategorisasi teks (atau juga dikenal dengan klasifikasi teks) adalah suatu task yang mengurutkan kumpulan dokumen D kedalam kategori yang telah ditentukan secara otomatis ke dalam kategori C. Dalam kategorisasi teks salah satu prosesnya adalah
Novendar Cahyo Pratama
core
Random walk term weighting for information retrieval
, 2007 We present a way of estimating term weights for Informa-tion Retrieval (IR), using term co-occurrence as a measure of dependency between terms. We use the random walk graph-based ranking algorithm on a graph that encodes terms and co-occurrence ...
Roi Blanco, Christina Lioma
core +1 more source
An Investigation of Term Weighting Approaches for Microblog Retrieval [PDF]
, 2012 The use of effective term frequency weighting and document length normalisation strategies have been shown over a number of decades to have a significant positive effect for document retrieval. When dealing with much shorter documents, such as those obtained from microblogs, it would seem intuitive that these would have less benefit.
Paul Ferguson +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source