Results 111 to 120 of about 2,288,930 (289)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Synthesis of Control of Terminal Acceleration of Spatial Rotations [PDF]
Among the problems of Adaptive Terminal Control, one of the most important is the problem of control of acceleration process of moving objects. Two cases are discussed: Control with arbitrary terminal acceleration and control with certain value of ...
Cabir Ergüven
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
SensorsWith the continuous improvement of remote sensing satellite resolution, laser communication technology has gained significant traction. The pointing accuracy of ground-based laser communication terminals is critical for the stability of satellite–ground ...
Wenyan Li +6 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Jurnal Teknik SipilBandung was chosen as a pilot area for Indonesian Mass Transit (MASTRAN) project to increase urban mobility and accessibility. With this MASTRAN project, public transportation nodes should be accessible by all modes, one of which is walking.
Octaviani Nur Rahmawati +2 more
doaj
Passenger terminal safety: simulation modelling as decision support tool
, 2016 The paper demonstrates the possibility of using simulation modelling for improving the processes of managing the development of the terminal at a strategic level, taking into account, first of all, security and safety aspects of quality of services.
Zemljanikins, Valerijs +3 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Memo re: Fort Worth Air Terminal, Inc.
, 1953 Memo regarding the funding, contracts, construction and operational costs of the Fort Worth Air Terminal ...
Fort Worth Air Terminal, Inc.
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source