Results 91 to 100 of about 2,056,194 (301)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A verification methodology for EVDO access terminal physical layer software
上海师范大学学报. 自然科学版, 2017 A simulation system to verify EVDO terminal physical layer software is proposed,which could simulate the actual behaviors of all hardware and software modules in hardware circuit board,and network the side behaviors associated to the terminal physical ...
Hou Haiyan, Jiang Letian
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Study of possibilities to establish regional transport terminal in Kaunas [PDF]
Transport, 2007 The article describes the creation of regional transport terminals and their usage as a tool to control material flows in the distribution channels. In the first part of the article the authors analyze the role of intermodal transport terminal within ...
G. Labanauskas, R. Palšaitis
doaj
Probabilistic termination versus fair termination
Theoretical Computer Science, 1989 The probabilistic almost everywhere termination of concurrent programs is proved to be expressible by a \(\Pi^ 0_ 2\) arithmetic formula and hence it has the complexity equivalent to that of deterministic program termination. This is much simpler then the \(\Pi^ 1_ 1\) complexity of ``fair'' termination.
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Research into the methods of analysing the productivity indicators of transport terminals [PDF]
Transport, 2009 The measurement of terminal productivity is the issue of extreme importance to both terminal owners and management and customers. As the sector of transport is highly intensive in terms of investments into the infrastructure, the productivity of a ...
I. Jaržemskienė
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source