Results 91 to 100 of about 2,288,930 (289)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Research into the methods of analysing the productivity indicators of transport terminals [PDF]

open access: yesTransport, 2009
The measurement of terminal productivity is the issue of extreme importance to both terminal owners and management and customers. As the sector of transport is highly intensive in terms of investments into the infrastructure, the productivity of a ...
I. Jaržemskienė
doaj  

Terminated [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2014
F R, Rosendaal, P H, Reitsma
openaire   +2 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Terminal City Dispatches [PDF]

open access: yes, 1998
Photocopy of a Terminal City Magazine review for a Satina Saturnina performance at The Brickyard.

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Terminal Lucidity: Envisioning the Future of the Terminal

open access: yes2025 IEEE/ACM 33rd International Conference on Program Comprehension (ICPC)
The Unix terminal, or just simply, the terminal, can be found being applied in almost every facet of computing. It is available across all major platforms and often integrated into other applications. Due to its ubiquity, even marginal improvements to the terminal have the potential to make massive improvements to productivity on a global scale.
Michael MacInnis   +2 more
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Research on multi-branch residual connection spectrum image classification based on attention mechanism

open access: yesScientific Reports
The acoustic spectrogram arranges the frequencies in the sound along the frequency spread, and translates the spectral changes into the intensity, wavelength and frequency of the electrical signals.
Zhong Xiaohui   +4 more
doaj   +1 more source

Proof Pearl: The Termination Analysis of Terminator [PDF]

open access: yes, 2007
TERMINATOR is a static analysis tool developed by Microsoft Research for proving termination of Windows device drivers written in C. This proof pearl describes a formalization in higher order logic of the program analysis employed by Terminator, and verifies that if the analysis succeeds then program termination logically follows.
openaire   +2 more sources

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