Results 81 to 90 of about 2,056,194 (301)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Terminal care. Home terminal care.
在宅ターミナルケアは家族の負担はあるものの患者にとっては贅沢な医療である.現在の日本で在宅医療を行うには,まだまだ多くの問題がある.しかしながら,患者,家族がそれを望む以上,医療者も行政もそれに応えるシステムをつくる時期にきていることも事実である.在宅ターミナルケアでは患者のみならず家族の身体的・精神的ケア,インフォームドコンセント,また臨死期の対応など多くの課題を抱えている.本稿ではそれらについて考察した.
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and application of UAV-based intelligent inspection system for LNG terminals
The safe and stable operation of liquefied natural gas (LNG) terminals, as critical energy infrastructure, is essential. To address the challenges of inefficiency, high workload, and safety risks associated with manual inspections, a "5G + Unmanned ...
Qingqiong TANG, Kun WANG, Huailei ZHENG
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Proof Pearl: The Termination Analysis of Terminator [PDF]
TERMINATOR is a static analysis tool developed by Microsoft Research for proving termination of Windows device drivers written in C. This proof pearl describes a formalization in higher order logic of the program analysis employed by Terminator, and verifies that if the analysis succeeds then program termination logically follows.
openaire +1 more source

