Results 61 to 70 of about 2,288,930 (289)

Engineered dityrosine-bonding of the RSV prefusion F protein imparts stability and potency advantages

open access: yesNature Communications
Viral fusion proteins facilitate cellular infection by fusing viral and cellular membranes, which involves dramatic transitions from their pre- to postfusion conformations.
Sonal V. Gidwani   +13 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Terminal cranes unloading Liberty ships.

open access: yes, 1944
Terminal cranes unloading Liberty ships loaded with iron ore from North Africa. The open storage area in the foreground had recently been cindered and is now suitable for open storage purposes.
Wilmington Marine Terminal
core   +2 more sources

Termination Analysis by Learning Terminating Programs [PDF]

open access: yes, 2014
We present a novel approach to termination analysis. In a first step, the analysis uses a program as a black-box which exhibits only a finite set of sample traces. Each sample trace is infinite but can be represented by a finite lasso. The analysis can "learn" a program from a termination proof for the lasso, a program that is terminating by ...
Matthias Heizmann   +2 more
openaire   +4 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Assumptions of small-scale intermodal transport [PDF]

open access: yesTransport, 2008
The aim of the article is to present the alternative to the very well known hub and spoken approach to intermodality when freight scale is small. When usually the blocked trains operate between two big intermodal hubs, here the concept of on-line ...
A. Jaržemskis
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Rho-dependent terminators and transcription termination [PDF]

open access: yesMicrobiology, 2006
Rho-dependent transcription terminators participate in sophisticated genetic regulatory mechanisms, in both bacteria and phages; they occur in regulatory regions preceding the coding sequences of genes and within coding sequences, as well as at the end of transcriptional units, to prevent readthrough transcription.
openaire   +2 more sources

Quelques enjeux de sécurité, juridiques, économiques, et énergétiques des blockchains

open access: yes, 2023
Pour avancer les réflexions et les recherches sur les blockchains (chaînes de blocs) grâce à des points de vue et disciplines complémentaires, nous accueillons dans ce numéro de la revue Terminal, sept analyses des enjeux des blockchains, menées par des ...
De Filippi, Primavera   +9 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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