Results 51 to 60 of about 2,288,930 (289)

An Efficient Genetic Algorithm to Solve the Intermodal Terminal Location problem [PDF]

International Journal of Supply and Operations Management, 2014
The exponential growth of the flow of goods and passengers, fragility of certain products and the need for the optimization of transport costs impose on carriers to use more and more multimodal transport.
Mustapha Oudani, Ahmed El Hilali Alaoui, Jaouad Boukachour   +2 more
doaj   +1 more source

TIC & handicap

, 2014
International audienceCe numéro spécial de la revue Terminal fait le point sur la contribution des TIC à l'amélioration des conditions de vie des personnes en situation de ...
Balin, Philippe, Gautier, Henri, Fichten, Catherine S., Pinède, Nathalie, Lavenue, Jean-Jacques, Lespinet-Najib, Véronique, André, Jean-Marc, Bacquelé, Vanessa, Mithout, Anne-Lise, Panico, Robert, Caouette, Martin, Marmilloud, Anne-Claire, Budd, Jillian, Garnier, Hervé, Chirié, Véronique, Lussier-Desrochers, Dany, Silicani, Jean-Ludovic, GOSSART, Cédric, Liquète, Vincent, Belio, Christian, Plichon, Romain, Demontoux, François, Nguyen, Mai Nhu, Dalle, Patrice, Asuncion, Jennison V., Fouquet, Yannick, Roche, Amélie, Vétois, Jacques, Fermingier, Isabelle, Demanes, Valérie   +29 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Left termination turned into termination

Theoretical Computer Science, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

How Common is the Common Law? Some Differences and Similarities in British and American Superior Court Decisions

Revista Alicantina de Estudios Ingleses, 2015
American law and English law belong to the same legal tradition, the common law, characterized by a case-law system based on judicial decisions and the rule of precedent.
Del-Bove, Marion Charret, Francoz-Terminal, Laurence   +1 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Wilmington Marine Terminal, scrapbook of photographs, 1942-1945

, 1942
Terminal worker loading cargo into a railroad car using a ...
Wilmington Marine Terminal
core   +2 more sources