Results 21 to 30 of about 103,354 (261)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Ringer lactate - the magical fluid
Research and Humanities in Medical Education, 2020 This article narrates my personal encounter with a terminally ill cancer patient at our rural clinic. I learned a lot from the experience. It made me reflect on the importance of palliative care in terminally ill patients and the practical difficulties ...
Vinod H Krishnamoorthy
doaj
Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro +10 more
wiley +1 more source
THE CLINICAL ROLES OF PSYCHOLOGISTS IN END-OF-LIFE CARE: A NEW HORIZON IN INDIAN PALLIATIVE CARE
The Anatolian Journal of Family Medicine, 2018 Among all the various existing skills needed in palliative end-of-life care, none is more important the ability to communicate effectively. Terminal ill experience is the time when patients were overwhelmed with several emotional and psychological ...
Vaiphei Suantak Demkhosei +1 more
doaj +1 more source
Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis
Arthritis Care &Research, Accepted Article.Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham +14 more
wiley +1 more source
The educational challenge of End-of-Life conversations for our junior doctors
Archives of Medicine and Health Sciences, 2018 Background: In current medical practice we face an increasing array of possible medical interventions, multi-morbid patients and an ageing population.
Josephine Suzanne Thomas +1 more
doaj +1 more source
Psychiatry and Terminal Illness [PDF]
The Canadian Journal of Psychiatry, 2000 Objective: To provide an overview of the palliative care literature salient to the psychiatric aspect of end-of-life care. Method: A literature review was conducted, targeting primarily empirical studies that addressed the following topics: 1) psychological issues pertaining to life-threatening conditions; 2) family issues in the context of palliative ...
openaire +2 more sources
Advanced Functional Materials, EarlyView.The layer‐by‐layer (LbL) assembly of coordination solids, enabled by the surface‐mounted metal‐organic framework (SURMOF) platform, is on the cusp of generating the organic counterpart of the epitaxy of inorganics. The programmable and sequential SURMOF protocol, optimized by machine learning (ML), is suited for accessing high‐quality thin films of ...
Zhengtao Xu +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
Sensorized Engineered Tissues with Built‐in Thermoregulation and Nutrient Supply
Advanced Functional Materials, EarlyView.This work introduces a granular hydrogel‐based tissue engineering platform that includes a closed‐loop temperature control to maintain 37°C and sustainably releases nutrients, thereby enabling cells to retain a high viability even if stored at room temperature for up to 24 h.
Antonia Georgopoulou +5 more
wiley +1 more source