Results 41 to 50 of about 142,095 (261)

Inverse problems for discrete Hermite nabla difference equation

open access: yesApplied Mathematics in Science and Engineering
Inverse problems are studied for discrete Hermite equations with nabla difference including initial value, terminal value and Sturm–Liouville problems. A quantitative study is conducted to obtain the solution.
B. Shiri, Y. Guang, D. Baleanu
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

DECREASING OF MECHANISMS DYNAMIC LOADING AT THE TRANSIENT STATE

open access: yesNauka ta progres transportu, 2015
Purpose. It is necessary to select modes of motion to reduce the dynamic loads in the mechanisms. This choice should be made on optimization basis. The purpose of research is to study methods of synthesis regimes of mechanisms and machines motion that ...
V. S. Loveikin, Yu. O. Romasevich
doaj   +1 more source

Fault current compensations in resonant grounded distribution systems to mitigate powerline bushfires using a nonsingular terminal sliding model controller

open access: yesIET Generation, Transmission & Distribution, 2022
A fault current compensation technique is proposed in this paper for resonant grounded power distribution systems in bushfire prone areas. Arc suppression devices with residual current compensation inverters are used to compensate fault currents due to ...
Tushar Kanti Roy, Md Apel Mahmud
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Analytic solutions and complete markets for the Heston model with stochastic volatility

open access: yesElectronic Journal of Differential Equations, 2018
We study the Heston model for pricing European options on stocks with stochastic volatility. This is a Black-Scholes-type equation whose spatial domain for the logarithmic stock price $x\in \mathbb{R}$ and the variance $v\in (0,\infty)$ is the half ...
Benedicte Alziary, Peter Takac
doaj  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Optimal excess of loss reinsurance-barrier dividend strategies with investment

open access: yesShenzhen Daxue xuebao. Ligong ban, 2022
The optimal barrier dividend problem under excess of loss reinsurance strategy has rarely been studied so far. We combine the risk factors such as market friction and terminal residual value with risk investment and risk control strategy, and study the ...
SUN Zongqi   +3 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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