Results 51 to 60 of about 884,665 (267)

PECULIARITIES OF FORMING VALUE ORIENTATIONS OF RURAL SCHOOLCHILDREN

open access: yesВестник Кемеровского государственного университета, 2013
Value orientations of rural schools’ senior students are considered in the paper. The results of the research conducted with M. Rokeach’s technique of studying value orientations are presented.
T. V. Vasilieva
doaj  

Literature Values of Terminal Half-Lives of Clozapine are Dependent on the Time of the Last Data Point

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2014
The pharmacokinetics of clozapine is a subject of intensive research because of its narrow therapeutic window and susceptibility to drug-drug interactions.
Jim Fang, Karen Mosier
doaj   +1 more source

Representation of the Value Orientations of a Stranger Depending on the Method of the Face Imaging

open access: yesЭкспериментальная психология, 2022
The observers’ ideas about the value orientations of visual communicants were experimentally studied. The subjects were sequentially presented in random order with the faces of people depicted in photographs and artistic portraits.
V.A. Barabanschikov, A.S. Shunto
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases

open access: yesLife Science Alliance, 2023
The design of a constitutively active form of the C-terminal kinase domain of the p90 ribosomal S6 kinase 2 (RSK2) is described, and this is based on a phosphomimetic mutation and a C-terminal truncation, yielding a high kinase activity.
Marlene Uglebjerg Fruergaard   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

VALUE ORIENTATIONS OF TEENAGERS WITH DIFFERENT LEVELS OF EMOTIONAL INTELLIGENCE

open access: yesRussian Journal of Education and Psychology
Background. The formation of values in adolescence is one of the priority tasks of school education and upbringing, since it is values that determine a person's relationship with society.
Yulia N. Anisimova   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

DYNAMICS OF VITAL VALUES OF ADOLESCENTS AND A PROBLEM OF CORRUPTION IN POST-SOVIET RUSSIA

open access: yesОбразование и наука, 2016
The purpose of the article is to show immanent interrelation between structure of terminal and tool vital values of adolescents of the Post-Soviet period and predisposition to perpetrate of corruption actions. Methods.
Pyotr N. Kondrashov
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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