Results 101 to 110 of about 1,648,060 (377)

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

open access: yesAdvanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André   +3 more
wiley   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients

open access: yesClinical Pharmacokinetics, 2015
Background and ObjectiveMorphine dosing can be challenging in terminally ill adult patients due to the heterogeneous nature of the population and the difficulty of accurately assessing pain during sedation. To determine the pharmacokinetics of morphine,
Linda G W Franken   +7 more
semanticscholar   +1 more source

Channel Estimation Method and Phase Shift Design for Reconfigurable Intelligent Surface Assisted MIMO Networks [PDF]

open access: yesarXiv, 2019
In this paper, we investigate channel estimation for a large intelligent surface (LIS) aided multiple-input multiple-output (MIMO) communication system. Due to the close proximity of communication devices and LIS terminal, the desired channels can be modeled as line-of-sight channels which are ill-conditioned.
arxiv  

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

open access: yesAdvanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang   +5 more
wiley   +1 more source

Washington v. Glucksberg: Influence of the Court in Care of the Terminally Ill and Physician Assisted Suicide [PDF]

open access: yes, 2001
This Note will examine current issues pertaining to the medical care of the terminally ill individual, particularly with respect to palliative care and how the continuum of medical care incorporates the voluntary termination of a patient\u27s life.
King, Philip
core   +3 more sources

What a wish to die can mean: reasons, meanings and functions of wishes to die, reported from 30 qualitative case studies of terminally ill cancer patients in palliative care

open access: yesBMC Palliative Care, 2014
BackgroundDespite research efforts over recent decades to deepen our understanding of why some terminally ill patients express a wish to die (WTD), there is broad consensus that we need more detailed knowledge about the factors that might influence such ...
K. Ohnsorge, H. Gudat, C. Rehmann-Sutter
semanticscholar   +1 more source

SemiCompRisks: An R Package for Independent and Cluster-Correlated Analyses of Semi-Competing Risks Data [PDF]

open access: yesarXiv, 2018
Semi-competing risks refer to the setting where primary scientific interest lies in estimation and inference with respect to a non-terminal event, the occurrence of which is subject to a terminal event. In this paper, we present the R package SemiCompRisks that provides functions to perform the analysis of independent/clustered semi-competing risks ...
arxiv  

Self‐organized Criticality in Neuromorphic Nanowire Networks With Tunable and Local Dynamics

open access: yesAdvanced Functional Materials, EarlyView.
Memristive nanowire networks (NWNs) are shown to be electrically tunable to a critical state where specific local dynamics evaluated by multiterminal characterization are exploited as feature selection in nonlinear transformation (NLT) tasks.
Fabio Michieletti   +3 more
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

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