Results 191 to 200 of about 1,667,342 (377)

Data‐Driven Multi‐Objective Optimization of Large‐Diameter Si Floating‐Zone Crystal Growth

Advanced Theory and Simulations, EarlyView.
This study presents a surrogate‐based Multi‐Objective Optimization framework for Floating Zone silicon crystal growth. An ensemble of Neural Networks is trained on simulation data and combined with Genetic Algorithms to explore trade‐offs in process parameters.
Lucas Vieira, Milena Petković, Robert Menzel, Natasha Dropka   +3 more
wiley   +1 more source

Bleeding risk of terminally ill patients hospitalized in palliative care units: the RHESO study

Journal of Thrombosis and Haemostasis, 2017
B. Tardy, S. Picard, F. Guirimand, C. Chapelle, M. D. Delerue, T. Celarier, J. Ciais, P. Vassal, S. Salas, M. Filbet, J. Gomas, A. Guillot, J. Gaultier, A. Merah, A. Richard, S. Laporte, L. Bertoletti   +16 more
semanticscholar   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Sarcopenia in Terminally Ill Patients with Cancer: Clinical Implications, Diagnostic Challenges, and Management Strategies. [PDF]

J Hosp Palliat Care
Go SI, Kang MH, Kim HG.
europepmc   +1 more source

Psychological Intervention on Reducing Stress of Nurses Caring for Terminally Ill Cancer Patients: A Quasi-Experimental Study. [PDF]

Alpha Psychiatry, 2023
Lv X.
europepmc   +1 more source

Assessing the Decision-Making Capacity of Terminally Ill Patients with Cancer.

The American journal of geriatric psychiatry, 2017
E. Kolva, B. Rosenfeld, R. Saracino
semanticscholar   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Caring for terminally Ill patients: the impact on oncologists. [PDF]

BMC Palliat Care
Somasundaram N, Ibrahim H, Govindasamy R, Hamid NABA, Ong SYK, Krishna LKR.   +5 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source