Results 281 to 290 of about 1,667,342 (377)

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Simultaneous occurrence of transient global amnesia and Takotsubo syndrome triggered by caring for a terminally ill relative. [PDF]

Clin Case Rep
Stöllberger C, Finsterer J.
europepmc   +1 more source

Nutrition, Hydration and Cost Containment [PDF]

, 1986
Diamond, Eugene F.
core   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

Advanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, Shuran Tan, Yumei Gao, Tong Liu, Si Sun, Xiaoman Wang, Yiping Wen, Liqiong Cai, Shi Du, Yuan Zhang, Jing Cai   +19 more
wiley   +1 more source

Aligned Nanostructures Resolve Zn2+ Transport Bottlenecks via Interfacial Kinetics–Diffusion Coupling in Aqueous Zinc‐Ion Batteries

Advanced Science, EarlyView.
It is revealed that limited solid‐state Zn2⁺ diffusion within the cathode leads to interfacial Zn2⁺ accumulation, forming a transport bottleneck that distorts Zn2⁺ flux directionality. Through advanced analytical techniques, including in situ electrochemical impedance spectroscopy (EIS), distribution of relaxation time (DRT) analysis, and COMSOL ...
Juyeon Han, Eunha Seo, Subeen Park, Se Hun Lee, Jeeyoung Yoo   +4 more
wiley   +1 more source

Nursing-care for family caregivers of terminally ill cancer patients to enhance preparedness for death. [PDF]

Nagoya J Med Sci
Unesoko A, Ozawa N, Sugimura A, Sato K, Ando S.   +4 more
europepmc   +1 more source

Ageing, illness and terminal care

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2010
openaire   +3 more sources

Preparing for Loss: A Psychoeducation and Support Group Curriculum for Emerging Adults With Anticipatory Grief Who Have a Terminally Ill Parent

, 2016
Mara D. Locketz
openalex   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source