Results 51 to 60 of about 1,667,342 (377)

The Necessary Right of Choice for Physician-Assisted Suicide [PDF]

open access: yes, 2017
Research-based paper on the importance of the right for terminally ill patients facing a painful death to be able to choose how they end their ...
Ullman, Kerry E.
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Nurses’ Caring Behavior for Terminally Ill Pediatric Patients.

open access: yesJournal of Health Science and Medical Research (JHSMR), 2011
Objective: 1) To describe nurses’ caring behavior for terminally ill pediatric patients 2) To identify the relationships between nurses’ caring behavior for terminally ill pediatric patients and personal factors of nurses.
Pranee Rattanaudom, Waraporn Kowthaisong
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Suspending Informed Consent

open access: yesVoices in Bioethics, 2014
The notion of suspended human animation has long been a topic in science fiction. Whether it is transporting human astronauts to far-off planets or freezing bodily processes for thousands of years, humans have been obsessed.
Dallas M. Ducar
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Facing death in the clinical practice: a view from nurses in Mexico

open access: yesSalud Pública de México, 2017
Objective. To explore the views of nurses on death in their practice, and their perception about physicians’ actions dealing with terminally ill patients. Materials and methods.
Ma. Luisa Marván   +3 more
doaj   +1 more source

The assessment of spiritual well-being in cancer patients with advanced disease: which are its meaningful dimensions?

open access: yesBMC Palliative Care, 2020
Background Spirituality is particularly important for patients suffering from life-threatening illness. Despite research showing the benefits of spiritual assessment and care for terminally ill patients, their spiritual needs are rarely addressed in ...
Elisa Rabitti   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Quality of life

open access: yesКонсультативная психология и психотерапия, 2015
Metropolitan Anthony was frequently invited to speak by medical institutions, particularly by those caring for terminally ill or dying. In his talk he approaches the notion of the quality of life from an unexpected angle.
Surozhskij A.
doaj   +1 more source

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