Results 61 to 70 of about 1,667,342 (377)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Terminal Illness

open access: yes, 2017
Use of the term “terminal illness” has been waning in the literatures of the social and health sciences since the late 20th century, due in part to the increase in the number of medical treatment options available to attempt to postpone dying and death.
openaire   +2 more sources

A role for doctors in assisted dying? An analysis of legal regulations and medical professional positions in six European countries [PDF]

open access: yes, 2008
An extensive debate about assisted suicide and euthanasia has been taking place in westernized countries during the last twenty years. Traditionally, the medical profession has maintained a clear distance from euthanasia and assisted suicide, but this ...
Bosshard, G.   +5 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Palliative Care for Terminally Ill Patients Among Nurses and Caregivers in Songklanagarind Hospital

open access: yesJournal of Health Science and Medical Research (JHSMR), 2013
Objective: 1) to study the level of nurses’ perception about palliative care for terminally ill patients, 2) to study the level of caregivers’ perception about palliative care for terminally ill patients, and 3) to compare perception level among nurses ...
Sirin Sastranuruk   +1 more
doaj  

Parents' Voices Supporting Music Therapy within Pediatric Palliative Care

open access: yesVoices, 2005
It has been my experience that parents are willing and open to express their voices to promote and advocate for music therapy services for their terminally ill children.
Kathryn Lindenfelser
doaj   +1 more source

Prevalence of neuropathic pain in terminally ill patients with cancer admitted to a general ward: a prospective observational study

open access: yesJournal of International Medical Research, 2021
Objectives To determine the prevalence of neuropathic pain among terminally ill patients with cancer admitted to a general ward, using the International Association for the Study of Pain algorithm.
Ryota Yanaizumi   +5 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Meaning in Life of Terminally Ill Parent with Young Children – A Quantitative Evaluation with SMiLE [PDF]

open access: green, 2021
Henning Cuhls   +4 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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