Results 71 to 80 of about 1,648,060 (377)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Quality of life

open access: yesКонсультативная психология и психотерапия, 2015
Metropolitan Anthony was frequently invited to speak by medical institutions, particularly by those caring for terminally ill or dying. In his talk he approaches the notion of the quality of life from an unexpected angle.
Surozhskij A.
doaj   +1 more source

Telling patients the truth [PDF]

open access: yes, 2005
'And you shall know the truth, and the truth shall make you free' (John 8:32) One of the dilemmas that any practitioner attending a seriously sick/ terminally ill patient experiences is whether he should tell the patient all the truth about the ...
Soler, Denis
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Prevalence of neuropathic pain in terminally ill patients with cancer admitted to a general ward: a prospective observational study

open access: yesJournal of International Medical Research, 2021
Objectives To determine the prevalence of neuropathic pain among terminally ill patients with cancer admitted to a general ward, using the International Association for the Study of Pain algorithm.
Ryota Yanaizumi   +5 more
doaj   +1 more source

Palliative care for terminally ill inmates: Does the state have a legal obligation? [PDF]

open access: yes, 2012
‘We ought to give those who are to leave life … the terminally ill … the same care and attention that we give those who enter life – the new-born.’1 In this article it is contended that terminally ill inmates have a right to palliative care and that ...
Albertus, Chesne
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Parents' Voices Supporting Music Therapy within Pediatric Palliative Care

open access: yesVoices, 2005
It has been my experience that parents are willing and open to express their voices to promote and advocate for music therapy services for their terminally ill children.
Kathryn Lindenfelser
doaj   +1 more source

Introductory Remarks of Panel II: Legal, Medical, and Ethical Considerations for the Future of Physician-Assisted Suicice Symposium: Physician-Assusted Suicide: Legal Rights in Life and Death: Introductory Remarks of Panel II: Legal, Medicial, and Ethical Considerations for the Future of Physician-Assisted Suicide [PDF]

open access: yes, 1996
Once the Supreme Court issues it decision in the cases of Quill v. Vacco1 and Compassion in Dying v. Washington2 regarding the constitutionality of outlawing physician-assisted suicide for competent and terminally ill persons, the tension surrounding ...
Hernandez, Tanya K.
core   +1 more source

Voluntary Euthanasia for the Terminally Ill [PDF]

open access: yes, 2021
A human comes into the world at birth. It is a natural beginning that progresses to a natural end. Human beings, unlike other animals, have intelligence and insight about their life cycle process.
Hamilton, Elizabeth
core   +1 more source

Home - About - Disclaimer - Privacy