Results 81 to 90 of about 1,648,060 (377)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Nurses’ Moral Sensitivity Regarding the Terminally Ill
Investigación y Educación en Enfermería, 2019 Objective. The purpose, herein, was to determine the moral sensitivity of nurses when caring for terminally ill patients. Methods. Descriptive study conducted in the city of Cartagena (Colombia) with the participation of 118 nurses with minimum ...
Yolima Carmona González +1 more
doaj +1 more source
Effects of dignity therapy on terminally ill patients: a systematic review.
Revista da Escola de Enfermagem da U S P, 2016 OBJECTIVE Analyzing the evidence of the effects of dignity therapy onterminally ill patients. METHOD A Systematic review of the literature conducted using the search strategy in six databases.
Suzana Cristina Teixeira Donato +3 more
semanticscholar +1 more source
Lipschitz Stability Estimate and Uniqueness in the Retrospective Analysis for The Mean Field Games System via Two Carleman Estimates [PDF]
arXiv, 2023 A retrospective analysis process for the mean field games system (MFGS) is considered. For the first time, Carleman estimates are applied to the analysis of the MFGS. Two new Carleman estimates are derived. They allow to obtain the Lipschitz stability estimate with respect to the possible error in the input initial and terminal data for a retrospective
arxiv
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
Palliative Care for Terminally Ill Patients Among Nurses and Caregivers in Songklanagarind Hospital
Journal of Health Science and Medical Research (JHSMR), 2013 Objective: 1) to study the level of nurses’ perception about palliative care for terminally ill patients, 2) to study the level of caregivers’ perception about palliative care for terminally ill patients, and 3) to compare perception level among nurses ...
Sirin Sastranuruk +1 more
doaj
JAMA pediatrics, 2016 Importance For clinicians caring for adolescent patients living with progressive, life-threatening illness, discussions regarding prognosis, goals of care, and treatment options can be extremely challenging.
A. Rosenberg +4 more
semanticscholar +1 more source
Needs of terminally ill cancer patients in an in-patient hospice unit [PDF]
, 1993 In Western Australia, in-patient hospice/palliative care units are caring for increasing numbers of terminally ill cancer patients. Hospice philosophy is based on the belief that the terminally ill patient in individual needs are of paramount importance.
Oldham, Marylynn C.
core +1 more source
Educational process in palliative care and the overhaul of thinking
Investigación y Educación en Enfermería, 2017 Objective. To know the contributions of the educational process in Palliative Care during the undergraduate level for the professional action of nurses in the care of patients at the end of life. Methods.
Karen Knopp de Carvalho +4 more
doaj +1 more source
WHY NOT TO MAKE A SMILE ON YOUR FACE AND YOUR PATIENT'S FACE [PDF]
Basrah Journal of Surgery, 2013 Every now and then, we face the problem of terminally ill patient or what looks incurable lesion, like disseminated malignancy. Certainly, all of us prefer not to face such a bitter reality. But sadly, this is unavoidable.
Thamir A. Hamdan
doaj +1 more source