Results 61 to 70 of about 71,560 (336)

Die Chemie und Biologie der Tetrodotoxin Naturstofffamilie

Angewandte Chemie, EarlyView.
Tetrodotoxin ist vor allem als das Gift des Kugelfisches bekannt, einer Delikatesse in der japanischen Küche. Seine Toxizität beruht auf der selektiven Blockade von NaV Kanälen, wie am Beispiel der NaV1.7 Pore dargestellt, wobei das DEKA Motiv hervorgehoben ist, das für die Durchlässigkeit von Natriumionen verantwortlich ist.
Benedikt Nißl, Marcel Mülbaier, Francesca Grisoni, Dirk Trauner, Marcel Bermúdez, Clemens Dialer, David B. Konrad   +6 more
wiley   +1 more source

Arginine in the FARM and SARM: A Role in Chain-Length Determination for Arginine in the Aspartate-Rich Motifs of Isoprenyl Diphosphate Synthases from Mycobacterium tuberculosis

Molecules, 2018
Isoprenyl chains are found in many important metabolites. These are derived from precursors of the appropriate length produced by isoprenyl diphosphate synthases (IDSs).
Raimund Nagel, Jill A. Thomas, Faith A. Adekunle, Francis M. Mann, Reuben J. Peters   +4 more
doaj   +1 more source

The effect of host structure on the selectivity and mechanism of supramolecular catalysis of Prins cyclizations. [PDF]

, 2015
The effect of host structure on the selectivity and mechanism of intramolecular Prins reactions is evaluated using K12Ga4L6 tetrahedral catalysts. The host structure was varied by modifying the structure of the chelating moieties and the size of the ...
Bergman, Robert G, Burford, Kristen N, Hart-Cooper, William M, Ozores, Haxel Lionel, Raymond, Kenneth N, Toste, F Dean, Triano, Rebecca M, Yaghoubi, Parastou, Zhao, Chen   +8 more
core   +2 more sources

Phylogenomic analyses and distribution of terpene synthases among Streptomyces

Beilstein Journal of Organic Chemistry, 2019
Terpene synthases are widely distributed among microorganisms and have been mainly studied in members of the genus Streptomyces. However, little is known about the distribution and evolution of the genes for terpene synthases.
Lara Martín-Sánchez, Kumar Saurabh Singh, Mariana Avalos, Gilles P. van Wezel, Jeroen S. Dickschat, Paolina Garbeva   +5 more
doaj   +1 more source

Volatile organic compounds: plant natural defense mechanisms against herbivorous arthropods and an opportunity for plant breeding of cotton

Scientia Agropecuaria, 2018
Plants’ natural defense mechanisms against herbivorous arthropods include the emission of volatile organic compounds (VOC). Nowadays field observations about plant-insect interactions are better understood thanks to the increasingly scientific ...
Ronald Villamar-Torres, Seyed Mehdi, Gabriel Liuba-Delfini, Luz García, Christopher-Robin Viot   +4 more
doaj   +1 more source

Biosynthese des Rotalgen‐Diterpens Peyssonnosol in Bakterien

Angewandte Chemie, EarlyView.
Zwei Terpensynthasen aus Anaerolineae‐Bakterien katalysieren die Biosynthese von Peyssonnosen‐artigen Diterpenen aus Rotalgen. Ortsgerichtete Mutagenese ermöglichte einen partiellen Funktionswechsel, der zur Bildung zusätzlicher Nebenprodukte führte.
Zhiyong Yin, Zhehui Hu, Kexin Yang, Guihu Lu, Georges B. Tabekoueng, Pingping Wu, Qi Luo, Juan Xu, Bernd Goldfuss, Jeroen S. Dickschat, Guangkai Bian   +10 more
wiley   +1 more source

Pushing the limits of concertedness. A waltz of wandering carbocations. [PDF]

, 2019
Among the array of complex terpene-forming carbocation cyclization/rearrangement reactions, the so-called "triple shift" reactions are among the most unexpected.
Castiñeira Reis, Marta, López, Carlos Silva, Nieto Faza, Olalla, Tantillo, Dean J   +3 more
core  

[Regulation of terpene metabolism] [PDF]

, 1989
OAK-B135 Research over the last four years has progressed fairly closely along the lines initially proposed, with progress-driven expansion of Objectives 1, 2 and 3. Recent advances have developed from three research thrusts: 1. Random sequencing of an enriched peppermint oil gland cDNA library has given access to a large number of potential pathway ...
openaire   +8 more sources

Interfacial Photoelectrochemistry in Organic Synthesis

Angewandte Chemie International Edition, Accepted Article.
Photoelectrodes have traditionally enjoyed widespread attention as heterogeneous catalysts for the activation of water and CO2 in energy research, while photoelectrochemistry with homogeneous molecular catalysts dominates the activations of more complex molecules in organic synthesis.
Gabriel Chan, Daria Corsi, Oleksandr Savateev, Paolo Giusto, Joshua Philip Barham   +4 more
wiley   +1 more source

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

Angewandte Chemie International Edition, EarlyView.
Tetrodotoxin is best known as the poison of the pufferfish, which is a delicacy in Japanese cuisine. Its toxicity arises from the selective blockage of NaV channels, which is depicted for the NaV1.7 pore, highlighting the DEKA motif, which permeates sodium ions.
Benedikt Nißl, Marcel Mülbaier, Francesca Grisoni, Dirk Trauner, Marcel Bermúdez, Clemens Dialer, David B. Konrad   +6 more
wiley   +1 more source