Results 151 to 160 of about 67,544 (332)

Chemically recyclable polyester thermosets from activated adipic acid and renewable polyols

open access: yesChemSusChem, Accepted Article.
This study outlines a method for producing chemically recyclable crosslinked polyesters using renewable polyols – glycerol and sorbitol – combined with adipic acid (AA), which is transformed/activated into a polyanhydride mixture prior to use. A three‐step procedure was designed: i) an acid‐catalyzed reaction of AA with non‐toxic isopropenyl acetate or
Davide Rigo   +5 more
wiley   +1 more source

Characterising a New Cannabis Trend: Extensive Analysis of Semi‐Synthetic Cannabinoid‐Containing Seizures From Germany

open access: yesDrug Testing and Analysis, EarlyView.
A LC–MS/MS method has been validated for analysis of semi‐synthetic cannabinoids (SSC) and selected phytocannabinoids in seizures. Further SSC‐derivatives were implemented into the method for qualitative detection. The methodology was applied to a sample collective (n = 80) including cannabis flowers, resins, edibles and vape liquids.
Marica Hundertmark   +4 more
wiley   +1 more source

Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography–High‐Resolution Mass Spectrometry (GC‐HRMS) and Liquid Chromatography–High‐Resolution Tandem Mass Spectrometry (LC‐HRMS/MS)

open access: yesDrug Testing and Analysis, EarlyView.
This study developed a comprehensive metabolomics workflow using GC‐HRMS and LC‐HRMS/MS and analyzed 35 CBD‐type cannabis flowers grown under varying conditions. Key discriminative compounds enabled classification by chemical phenotype and cultivation environment. The results showed that environmental factors influence chemical profiles, supporting the
Sandra N. Poetzsch   +3 more
wiley   +1 more source

Upcycling Food Waste: Ursolic Acid as Sustainable Feedstock

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This study presents a sustainable strategy to access 24 ursane‐type natural products from ursolic acid, derived from apple pomace waste. The method enables short syntheses (1–12 steps) with high yields (up to 98%). By upcycling food waste into valuable bioactive compounds, this work exemplifies green chemistry and supports circular economy principles ...
Timo A. Zschau   +5 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

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