Results 151 to 160 of about 35,127 (257)

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

STM investigation of atomic-scale structures of Ag/Au(111) surface. [PDF]

Nanoscale Adv
Kodama H, Nagai S, Lee M, Kim Y, Kazuma E.   +4 more
europepmc   +1 more source

Shimizu (Japan), tea terraces

, 1935
Tea terraces.
Read, Mary Jo
core  

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Topochemistry of Ammonium Perchlorate: How Surface Morphology Mediates Its Sublimation. [PDF]

J Phys Chem Lett
Felix LC, Penev ES, Sun M, Yakobson BI.
europepmc   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source

Real-Space Molecular Resolution Imaging of Graphite-Anchored MOF Surfaces via Atomic Force Microscopy at the Liquid-Solid Interface. [PDF]

Small Methods
Cucinotta A, Otake KI, Kitagawa S, Feyter S.   +3 more
europepmc   +1 more source

Philippines, office hut at Ifugao Rice Terraces of Cordillera Central Mountains in Banaue

, 1955
The fabulous Ifugao Rice Terraces at Banaue in northern Luzon. It took this tribe of Igorots 2,000 years to build them, according to this geological study.
Forman, Harrison, 1904-1978
core  

Quaternary landscape evolution of Apennines peri-Adriatic belt: Insights into climate and tectonics from the fluvial record. [PDF]

Sci Adv
Ruscitto V, Delchiaro M, Richard M, Iacobucci G, Piacentini D, Troiani F, Seta MD.   +6 more
europepmc   +1 more source

Osseoperceptive EMG Feedback Improves Grasp Force Control in Myoelectric Prosthetic Hands

Advanced Science, EarlyView.
Osseoperception is explored as a non‐invasive pathway for delivering sensory feedback in myoelectric prosthetic control. By encoding the user's electromyographic (EMG) signal through bone‐conducted stimulation, this approach enables predictive grasp force regulation.
Cristian Felipe Blanco‐Diaz, Strahinja Dosen, Leonardo Cappello   +2 more
wiley   +1 more source