Results 121 to 130 of about 1,455,714 (333)
, 2015 As a nationalistic concept, frontier refers to America\u27s westward expansion, which was propelled in the nineteenth century by Manifest Destiny. Culturally, frontier promises even more: the creation of communities, the development of markets and states,
Nanda, Aparajita
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Identités des Grecs pontiques et caucasiens : le rapport aux lieux et aux territoires
Cahiers Balkaniques: the Pontic Greeks and Caucasians came from a very mountainous region on the shores of the Black Sea, characterized by a fragmentation into parallel north-south valleys.
Michel Bruneau
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
La Frontière indigène Sud de l’Argentine : conflit de territoires et conflits d’intérêts
Amerika, 2015 Marginal area of the Hispanic colonization, the Río de la Plata is a specific case because of its Indian Frontier and seemed to have been at first of no great interest for the Conquerors.
Ghislaine Floury-Dagorn
doaj +1 more source
Stewart v. McIntosh, 4 H. & J. 233 (1816) [PDF]
, 2012 Stewart v. M’Intosh was argued during the time period of the Jay Treaty, the Quasi-War, the Haitian Revolution, and the War of 1812. The facts begin at the end of the 18th century and extend into the early 19th century.
Donnelly, Rhett
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2018 This article proposes to explore the government of the Portuguese empire in the seventeenth century, by turning our attention from the metropolitan institutions to the local governmental practices, and to take more into account the territorial dimension ...
Guida Marques
doaj +1 more source