Depression meets obesity: Co-occurrence patterns, temporal trends and socioeconomic correlates across 199 countries and territories. [PDF]
Yang Y +7 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Impact of Local Intravitreal Injection Delivery on Cost, Carbon Emissions, and Attendance in Yellowknife, Northwest Territories. [PDF]
Switzer A +3 more
europepmc +1 more source
Territorial competitiveness for territorial intelligence.
In this study I present the regional competitiveness factors for territorial intelligence. First, to this factors we must define the territorial units and the spatial indexes. Then we analize the factors of competitiveness which are on the one part quantitative indicators ont he other part qualitative indicators.
openaire +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Health and economic burdens of emerging infectious diseases in the USA, US territories and globally. [PDF]
Sevilla JP +12 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A National Review of the Interim Canada Dental Benefit: Analyzing the Uptake Among Uninsured Children Under 12. [PDF]
Goubran S +6 more
europepmc +1 more source

