Results 111 to 120 of about 997,893 (309)

Nationalism, territoriality and national territorial belonging

open access: yesPapers. Revista de Sociologia, 2010
La mayoría de los estudios sobre el nacionalismo entiende la nación como una colectividad cultural que se puede situar en términos históricos en la transición de la época premoderna a la moderna. Se ha prestado menos atención a consideraciones de espacio. En este contexto, este artículo propone que no podemos comprender totalmente tanto el nacionalismo
openaire   +7 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

La fabrique des territoires du « bien vieillir » : recompositions du thermalisme et gouvernement municipal en France. Le cas de Bagnoles de l’Orne (Normandie)

open access: yesLien Social et Politiques, 2017
Avec l’instauration de la Sécurité sociale et le remboursement des cures par l’Assurance maladie, les stations thermales françaises sont, au sortir de la Seconde Guerre mondiale, consacrées comme des territoires d’accompagnement des pathologies et ...
Adrien Sonnet   +2 more
doaj   +1 more source

Uncovering Proximity of Chromosome Territories using Classical Algebraic Statistics [PDF]

open access: yes, 2014
Exchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments rejoin with other fragments from other chromosomes.
Arsuaga, Javier   +3 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Le territoire viticole en France : de la destruction à la valorisation [PDF]

open access: yes
The surfaces devoted to the vine were reduced with the passing years. Under the effect of several phenomena that lead to lower consumption of wine, the decrease in vineyard area has led to a disintegration of rural and peri-urban area and reallocation of
Francoise Bourdon and Marie-Claude Pichery
core  

Re-emerging landscapes : militarised territories from the Cold War period [PDF]

open access: yes, 2018
This paper is part of my research that investigates the large-scale remains of military activities from the Cold War period. The aim of the research is to provide a meta-perspective on the post-militarised spaces and their different developmental ...
Stilinovic, Mladen
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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