Results 71 to 80 of about 335,645 (315)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
[Map of steamship routes in the Australia and the Pacific region] [cartographic material] /
, 1922 Draft map of Australia and the Pacific region showing all red route, Commonwealth line, steamship routes of Burns Philp, Eastern & Australian Steamship Company, A.U.S.N., Nippon Yusen Kaisha, Australian-Oriental, and Osaka-Soshen-Kaisha.; "Oct 1922 ...
Australia. Department of Home and Territories. Lands and Surveys Branch.
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
General map of the Northern Territory of Australia [cartographic material] /
, 1922 Map showing land holdings, gold mining areas, stock routes, isohyets and rainfall and telegraph line.
Australia. Department of Home and Territories. Northern Territory Branch.
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Identités des Grecs pontiques et caucasiens : le rapport aux lieux et aux territoires
Cahiers Balkaniques: the Pontic Greeks and Caucasians came from a very mountainous region on the shores of the Black Sea, characterized by a fragmentation into parallel north-south valleys.
Michel Bruneau
doaj +1 more source
A Territorial Contradiction [PDF]
, 2014 Spatial planning and environmental restoration are essential corollaries to the management of protected natural areas, however, without a sound awareness of the evolutionary consistency of biocoenoses, the harmonious integration between human activities and ecosystem preservation remains an unattainable utopia.
GUARINO, Riccardo +3 more
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Thinking beyond urban: Reconceiving Australia’s peri-urban territories
, 2021 The peri-urban spaces on the fringes of our cities are dynamic territories with a diverse array of sometimes competing functions, from wastewater treatment to agriculture.
Padgett Kjaersgaard, Sara ; https://orcid.org/
core
Nuevo mundo - Mundos Nuevos, 2018 This article proposes to explore the government of the Portuguese empire in the seventeenth century, by turning our attention from the metropolitan institutions to the local governmental practices, and to take more into account the territorial dimension ...
Guida Marques
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source