Results 141 to 150 of about 2,094,634 (340)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The Recognition Method of ‘bird's eye view' and the Rhetoric of Geo-body:Hometown, Territory, Nation in Lee Eun Sang's Writing

, 2014
Jiseung Roh
openalex   +1 more source

Virgin territory [PDF]

Nature, 2014
openaire   +2 more sources

Preface [PDF]

, 2017
Preface to the 2017 Annals of the Department of Methods and Models in Economics, Finance,Territory and Economic History, involuding a presentation of all the contirbutions in the ...
DE ROSE, Alessandra, Incelli, Ersilia Amedea   +1 more
core  

Narrative Review: Clinical Implications and Assessment of Frailty in Patients With Advanced CKD

Kidney International Reports
Frailty is a multidimensional clinical syndrome characterized by low physical activity, reduced strength, accumulation of multiorgan deficits, decreased physiological reserve, and vulnerability to stressors.
Alice L. Kennard, Nicholas J. Glasgow, Suzanne E. Rainsford, Girish S. Talaulikar   +3 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The Establishment of Sovereignty of the Mongol Khagan and the Golden Horde’s Khan on the Territory of Rus’

, 2018
Yuriy V. Seleznev
openalex   +1 more source

Design and application of species-specific primers to Quercus cerris roots’ identification in urban forests

Scientific Reports
Accurate species identification, the first crucial step for effective root studies, is a time-demanding, experience-based and error-prone process. Molecular methods are therefore needed to ensure this process, especially in urban settings where root ...
Daniele Fantozzi, Gabriella Sferra, Dalila Trupiano, Gabriella Stefania Scippa   +3 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source