Results 111 to 120 of about 1,021,966 (313)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Batchelor Institute of Indigenous Tertiary Education annual report 2005

open access: yes, 2005
Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)

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Regulation of Tertiary Education

open access: yesAgenda - A Journal of Policy Analysis and Reform, 2004
The provision of tertiary education is regarded by many as being vital to both the achievement of economic success and greater social equity. In recent years the trend in most countries has been to grant government education providers with greater institutional autonomy but at the same time subject them, and private providers, to formal regulation. The
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Batchelor Institute of Indigenous Tertiary Education annual report 2000

open access: yes, 2000
Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)

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ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Batchelor Institute of Indigenous Tertiary Education annual report 2010

open access: yes, 2010
Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)

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Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Batchelor Institute of Indigenous Tertiary Education annual report 2015

open access: yes, 2015
Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)

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LEAP Up – Transition to Tertiary Pilot Program

open access: yes, 2022
In 2020 Vision Australia implemented a Transition to Tertiary pilot program which was designed to prepare young people who are blind or have low vision for tertiary education.
Boys, Alexandra   +3 more
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