Results 121 to 130 of about 1,021,966 (313)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Batchelor Institute of Indigenous Tertiary Education annual report 2016
, 2016 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Batchelor Institute of Indigenous Tertiary Education annual report 2009
, 2009 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Batchelor Institute of Indigenous Tertiary Education annual report 2002
, 2002 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)
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International students: Sojourners or immigrants? A changing role for tertiary learning advisors. [PDF]
, 2009 Reforms to Australia's skilled migration policy since 1999 have led to a marked increase in the proportion of the skilled migration intake coming from former international students, in particular from students graduating from accounting programmes ...
Craven, EA
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Batchelor Institute of Indigenous Tertiary Education Graduation Ceremony
, 2000 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)
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